Jensen Vibeke Frøkjær
Afdeling for Mikrobiologi og Risikovurdering, Fødevareinstituttet, Danmarks Tekniske Universitet, Mørkhøj Bygade 26, 2860 Søborg, Denmark.
Ugeskr Laeger. 2011 Nov 7;173(45):2862-6.
In the Danish husbandry antimicrobial growth promoters were phased out 1994-2000 and the therapeutic use has been increasingly regulated. Hitherto, a minimum in therapeutic use was reached in 1997. The antimicrobial use in pigs increased by 44% during 2002-2009; a 12% decrease in second half of 2010 was likely due to the announcement of the "yellow card" regulation. From July 2010, a voluntary two years stop of cephalosporins use in pigs was realized, due to increasing occurrence of extended spectrum beta lactamase (ESBL) resistance in animal and meat isolates; highest levels of ESBL are observed in imported poultry.
在丹麦的畜牧业中，抗菌生长促进剂于1994年至2000年逐步淘汰，其治疗用途的监管也日益严格。迄今为止，1997年治疗用途达到最低水平。2002年至2009年期间，猪的抗菌药物使用量增加了44%；2010年下半年下降了12%，这可能是由于“黄牌”规定的宣布。自2010年7月起，由于动物和肉类分离株中广谱β-内酰胺酶（ESBL）耐药性的发生率不断增加，猪自愿停用头孢菌素两年；在进口家禽中观察到最高水平的ESBL。
