Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, CSB 812, Charleston, SC 29425, USA.
Clin Chest Med. 2011 Dec;32(4):827-38. doi: 10.1016/j.ccm.2011.08.009. Epub 2011 Oct 7.
Emerging from the past decade, there has been a diversification of options for the treatment of early-stage lung cancer. Video-assisted thoracoscopic surgery is now more widely performed, with oncologic outcomes equivalent to those with open thoracotomy. Although lobectomy remains the standard approach to surgical resection, lesser resections, such as segmentectomy and wedge resection, are considerations for some patients. Advances in surgical, radiation, and medical therapies continue to evolve. Future research questions will focus on comparing long-term outcomes with these modalities, including survival, as well as patient-centered endpoints, such as quality of life.
在过去十年中，早期肺癌的治疗选择出现了多样化。现在，电视辅助胸腔镜手术（video-assisted thoracoscopic surgery，VATS）的应用更加广泛，其肿瘤学结果与开胸手术相当。虽然肺叶切除术仍然是手术切除的标准方法，但对于某些患者，较小的肺切除术，如节段切除术和楔形切除术，也是一种考虑。外科、放射和药物治疗方面的进展仍在不断发展。未来的研究问题将集中在比较这些方法的长期结果，包括生存，以及以患者为中心的终点，如生活质量。
