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普萘洛尔在打哈欠预防中的应用:病例报告。

Propranolol in yawning prophylaxis: a case report.

机构信息

Research Center for Psychiatry and Behavioral Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Gen Hosp Psychiatry. 2012 May-Jun;34(3):320.e7-9. doi: 10.1016/j.genhosppsych.2011.09.021. Epub 2011 Nov 4.

DOI:10.1016/j.genhosppsych.2011.09.021
PMID:22055334
Abstract

OBJECTIVE

Yawning is a frequent behavior with circadian effects. Sometimes, its frequency is very high and it is disturbing. However, there is no evidence-based treatment for yawning.

METHOD

This is a case report of a man with severe yawning from about 2 years ago.

RESULTS

Yawning reduced after taking propranolol.

CONCLUSION

Current evidence suggests that propranolol may decrease yawning through its thermoregulation effect. It is worthwhile conducting controlled clinical trials to study whether propranolol is an effective treatment for yawning.

摘要

目的

打哈欠是一种具有昼夜节律影响的常见行为。有时,它的频率非常高,令人困扰。然而,目前还没有针对打哈欠的循证治疗方法。

方法

这是一例约 2 年前出现严重打哈欠的男性病例报告。

结果

服用普萘洛尔后打哈欠减少。

结论

目前的证据表明,普萘洛尔可能通过其体温调节作用减少打哈欠。值得进行对照临床试验,以研究普萘洛尔是否是治疗打哈欠的有效方法。

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PLoS One. 2022 Feb 4;17(2):e0263510. doi: 10.1371/journal.pone.0263510. eCollection 2022.
2
The thermoregulatory theory of yawning: what we know from over 5 years of research.打哈欠的体温调节理论:我们从 5 年多的研究中了解到了什么。
Front Neurosci. 2013 Jan 2;6:188. doi: 10.3389/fnins.2012.00188. eCollection 2012.