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本文引用的文献
1
Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A.
Genes Dev. 2011 Nov 1;25(21):2266-77. doi: 10.1101/gad.172296.111. Epub 2011 Oct 14.
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Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers.
Nat Rev Cancer. 2010 Jul;10(7):457-69. doi: 10.1038/nrc2876.
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Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases.
Annu Rev Biochem. 2010;79:155-79. doi: 10.1146/annurev.biochem.78.070907.103946.
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Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat Struct Mol Biol. 2010 Jan;17(1):38-43. doi: 10.1038/nsmb.1753. Epub 2009 Dec 20.
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Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.
Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008.
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Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.
Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18439-44. doi: 10.1073/pnas.0707292104. Epub 2007 Nov 14.
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Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.
Science. 2007 Oct 19;318(5849):447-50. doi: 10.1126/science.1149042. Epub 2007 Aug 30.
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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.
Nature. 2007 Oct 11;449(7163):731-4. doi: 10.1038/nature06145. Epub 2007 Aug 22.
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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat Struct Mol Biol. 2007 Aug;14(8):689-95. doi: 10.1038/nsmb1273. Epub 2007 Jun 24.
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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature. 2007 Jul 5;448(7149):87-91. doi: 10.1038/nature05971. Epub 2007 Jun 24.
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