Mishra Rakesh Kumar, Mishra Garima, Li M S, Kumar Sanjay
Department of Physics, Banaras Hindu University, Varanasi 221 005, India.
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Sep;84(3 Pt 1):032903. doi: 10.1103/PhysRevE.84.032903. Epub 2011 Sep 23.
Using the Langevin dynamics simulation, we have studied the effects of shear force on the rupture of short double-stranded DNA at different temperatures. We show that the rupture force increases linearly with chain length and approaches the asymptotic value in accordance with the experiment. The qualitative nature of these curves remains almost the same for different temperatures but with a shift in the force. We observe three different regimes in the extension of covalent bonds (backbone) under shear force.
通过朗之万动力学模拟,我们研究了剪切力在不同温度下对短双链DNA断裂的影响。我们表明,断裂力随链长线性增加,并根据实验趋近于渐近值。这些曲线的定性性质在不同温度下几乎保持相同,但力有偏移。我们观察到在剪切力作用下共价键(主链)延伸存在三种不同的状态。