Öztürk Çiğdem, te Slaa Alexander, Dolmans Dennis E J G J, Ho G H, de Vries Jolanda, Mulder Paul G H, van der Laan Lyckle
Department of Surgery, Amphia Hospital, Breda, The Netherlands.
Ann Vasc Surg. 2012 Apr;26(3):373-82. doi: 10.1016/j.avsg.2011.07.012. Epub 2011 Nov 6.
To examine the effects of peripheral bypass surgery on patients' quality of life (QoL) as well as to compare two treatment modalities to reduce postoperative edema with regard to patients' QoL.
This was a randomized controlled trial set in the department of vascular surgery in a nonacademic teaching hospital. Ninety-three patients (mean age, 70 years; 33% Rutherford 5-6), enrolled between August 2006 and September 2009, who underwent peripheral bypass surgery (autologous 57, polytetrafluoroethylene 36). Patients were assigned to intermittent pneumatic compression (n = 46) or to compression stockings (n = 47). The main outcome measure was QoL, measured with the World Health Organization Quality of Life assessment instrument (short form: WHOQOL-BREF).
QoL improved on the domain of Physical Health by 7.18 points (P < 0.001 [range, 0-100]) after 2 weeks and by 10.03 points (P < 0.001) after 3 months. Patients who received a polytetrafluoroethylene bypass scored 0.45 points (P = 0.0008 [range, 1-5]) lower at baseline on Global QoL than patients who received an autologous bypass. Type of bypass or edema treatment method did not affect the improvements. Edema did not correlate with QoL.
Improvement in QoL on the domain Physical Health following femoropopliteal bypass surgery was found as soon as 2 weeks after surgery. Improvement in QoL domains was not influenced by the type of bypass reconstruction. No specific effects of edema on QoL were detected.
研究外周血管搭桥手术对患者生活质量(QoL)的影响,并比较两种减少术后水肿的治疗方式对患者生活质量的影响。
这是一项在非学术性教学医院血管外科进行的随机对照试验。2006年8月至2009年9月期间,93例患者(平均年龄70岁;33%为卢瑟福分级5 - 6级)接受了外周血管搭桥手术(自体血管搭桥57例,聚四氟乙烯搭桥36例)。患者被随机分为间歇性气动压迫组(n = 46)或弹力袜压迫组(n = 47)。主要结局指标是生活质量,采用世界卫生组织生活质量评估工具(简表:WHOQOL - BREF)进行测量。
术后2周,身体健康领域的生活质量提高了7.18分(P < 0.001[范围0 - 100]),3个月后提高了10. < 0.001)。接受聚四氟乙烯搭桥的患者在基线时的总体生活质量得分比接受自体血管搭桥的患者低0.45分(P = 0.0008[范围1 - 5])。搭桥类型或水肿治疗方法不影响生活质量的改善。水肿与生活质量无关。
股腘动脉搭桥手术后2周,身体健康领域的生活质量即出现改善。生活质量领域的改善不受搭桥重建类型的影响。未检测到水肿对生活质量有特定影响。