Aviv J E, Lawson W, Bottone E J, Sachdev V P, Som P M, Biller H F
Department of Otolaryngology, Mount Sinai Medical Center, New York, NY 10029.
Arch Otolaryngol Head Neck Surg. 1990 Oct;116(10):1210-3. doi: 10.1001/archotol.1990.01870100104024.
The purpose of this article is to alert clinicians to a new pathogenic fungus of the paranasal sinuses called Exserohilum rostratum. Exserohilum species are one of the etiologic agents of phaeohyphomycosis, a constellation of entities caused by dematiaceous fungi. This class of fungal sinus infection has emerged only in the past decade; it occurs primarily in immunocompetent individuals and produces a tenacious, progressive pansinusitis. To our knowledge, this study describes the first case of multiple intracranial mucoceles secondary to E rostratum. The diagnostic workup includes computed tomography and magnetic resonance imaging followed by direct microscopic examination of tissue biopsy specimens. A craniotomy followed by a bilateral external ethmoidectomy was necessary for complete extirpation of the infected mucoceles. Aggressive surgical management of this mycotic infection is described.
本文旨在提醒临床医生注意一种名为喙突弯孢霉的鼻窦新致病真菌。弯孢霉属真菌是暗色丝孢霉病的病原体之一，暗色丝孢霉病是由暗色真菌引起的一组病症。这类真菌性鼻窦感染在过去十年才出现；它主要发生在免疫功能正常的个体中，并引发顽固的、进行性全鼻窦炎。据我们所知，本研究描述了首例继发于喙突弯孢霉的多发性颅内黏液囊肿病例。诊断检查包括计算机断层扫描和磁共振成像，随后对组织活检标本进行直接显微镜检查。为了彻底切除受感染的黏液囊肿，需要进行开颅手术，随后进行双侧外部筛窦切除术。本文描述了对这种霉菌性感染的积极手术治疗方法。
