Gloria Antonio, Ronca Dante, Russo Teresa, D'Amora Ugo, Chierchia Marianna, De Santis Roberto, Nicolais Luigi, Ambrosio Luigi
Institute of Composite and Biomedical Materials, National Research Council, Naples, Italy.
J Appl Biomater Biomech. 2011 May-Aug;9(2):151-63. doi: 10.5301/JABB.2011.8569.
Polymer-based composite materials are ideal for applications where high stiffness-to-weight and strength-to-weight ratios are required. From aerospace and aeronautical field to biomedical applications, fiber-reinforced polymers have replaced metals, thus emerging as an interesting alternative. As widely reported, the mechanical behavior of the composite materials involves investigation on micro- and macro-scale, taking into consideration micromechanics, macromechanics and lamination theory. Clinical situations often require repairing connective tissues and the use of composite materials may be suitable for these applications because of the possibility to design tissue substitutes or implants with the required mechanical properties. Accordingly, this review aims at stressing the importance of fiber-reinforced composite materials to make advanced and biomimetic prostheses with tailored mechanical properties, starting from the basic principle design, technologies, and a brief overview of composites applications in several fields. Fiber-reinforced composite materials for artificial tendons, ligaments, and intervertebral discs, as well as for hip stems and mandible models will be reviewed, highlighting the possibility to mimic the mechanical properties of the soft and hard tissues that they replace.
基于聚合物的复合材料非常适合需要高刚度重量比和强度重量比的应用。从航空航天领域到生物医学应用,纤维增强聚合物已经取代了金属,从而成为一种有趣的替代品。正如广泛报道的那样,复合材料的力学行为涉及微观和宏观尺度的研究,要考虑微观力学、宏观力学和层合理论。临床情况经常需要修复结缔组织,而使用复合材料可能适合这些应用,因为有可能设计出具有所需力学性能的组织替代物或植入物。因此,本综述旨在强调纤维增强复合材料对于制造具有定制力学性能的先进仿生假体的重要性,从基本原理设计、技术以及复合材料在多个领域的应用简要概述开始。将对用于人工肌腱、韧带和椎间盘以及用于髋关节柄和下颌骨模型的纤维增强复合材料进行综述,突出模仿它们所替代的软硬组织力学性能的可能性。