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沃思综合征作为下颌骨骨硬化症的一种诊断。

Worth syndrome as a diagnosis for mandibular osteosclerosis.

机构信息

Royal Derby Hospital, Derby, UK.

出版信息

Dentomaxillofac Radiol. 2011 Dec;40(8):531-3. doi: 10.1259/dmfr/71865631.

DOI:10.1259/dmfr/71865631
PMID:22065804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3528158/
Abstract

This case report presents an unusual incidental radiographic finding on a dental panoramic radiograph that caused diagnostic confusion. A 46-year-old female presented with symmetrical sclerotic cortical thickening of the anterior mandible visible on radiograph, with no other major clinical examination findings. The patient subsequently showed no change in radiographic appearance over a 6 year period. Based on this evidence, and the benign nature of the history, we propose a diagnosis of Worth syndrome. This report aims to clarify the difference in terminology and presentation of two conditions known to produce mandibular osteosclerosis: Worth syndrome and Van Buchem disease, both of which are often quoted synonymously in the literature.

摘要

本病例报告介绍了牙科全景片上一种不常见的偶然放射学发现,该发现导致了诊断混淆。一名 46 岁女性因下颌前骨对称性硬化性皮质增厚而就诊,影像学可见,其他主要临床检查未见异常。患者在 6 年期间,影像学表现无变化。根据这些证据以及良性的病史,我们提出 Worth 综合征的诊断。本报告旨在阐明两种已知引起下颌骨骨硬化的病症在术语和表现上的差异:Worth 综合征和 Van Buchem 病,这两种病症在文献中常被同义引用。

相似文献

1
Worth syndrome as a diagnosis for mandibular osteosclerosis.沃思综合征作为下颌骨骨硬化症的一种诊断。
Dentomaxillofac Radiol. 2011 Dec;40(8):531-3. doi: 10.1259/dmfr/71865631.
2
Worth syndrome "mandibular osteosclerosis" as an incidental finding: a report of 2 cases.Worth 综合征“下颌骨骨硬化症”作为偶然发现:2 例报告。
Dentomaxillofac Radiol. 2018 Dec;47(8):20180171. doi: 10.1259/dmfr.20180171. Epub 2018 Jul 20.
3
Autosomal dominant osteosclerosis.常染色体显性遗传性骨硬化症
Radiology. 1977 Nov;125(2):289-96. doi: 10.1148/125.2.289.
4
Gigantic dense bone island of the jaw.颌骨巨大致密性骨岛。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Jul;82(1):108-15. doi: 10.1016/s1079-2104(96)80387-8.
5
Autosomal dominant osteosclerosis.常染色体显性遗传性骨硬化症
Radiology. 1977 Nov;125(2):547-8. doi: 10.1148/125.2.547.
6
Oral radiographic and clinico-pathologic presentation of Erdheim-Chester disease: a case report.骨嗜酸性肉芽肿的口腔影像学及临床病理表现:一例报告
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 May;103(5):e79-85. doi: 10.1016/j.tripleo.2006.11.006. Epub 2007 Feb 20.
7
[On the circle of forms of sclerosing osteoses (author's transl)].论硬化性骨病的形态学分类(作者译)
Radiol Diagn (Berl). 1974;15(3):261-80.
8
Oral diagnosis. Mandibular radiopacities. Idiopathic osteosclerosis.口腔诊断。下颌骨致密影。特发性骨硬化症。
Gen Dent. 2007 Nov-Dec;55(6):591, 595.
9
Diffuse, increased radiodensity of the maxilla and mandible.上颌骨和下颌骨弥漫性放射性密度增加。
J Am Dent Assoc. 1985 Mar;110(3):381-2. doi: 10.14219/jada.archive.1985.0339.
10
Worth Syndrome-Patient Report, Diagnostic Work-Up, and Surgical Management of a Rare Craniofacial Entity.沃思综合征-患者报告、罕见颅面实体的诊断性检查和手术治疗。
J Craniofac Surg. 2023 May 1;34(3):e330-e331. doi: 10.1097/SCS.0000000000009259. Epub 2023 Mar 13.

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2
Worth syndrome "mandibular osteosclerosis" as an incidental finding: a report of 2 cases.Worth 综合征“下颌骨骨硬化症”作为偶然发现:2 例报告。
Dentomaxillofac Radiol. 2018 Dec;47(8):20180171. doi: 10.1259/dmfr.20180171. Epub 2018 Jul 20.

本文引用的文献

1
Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal.患有范布赫姆病(一种骨硬化性遗传病)的患者,其骨形成标志物升高,骨密度更高,且比正常人具有更大的衍生极惯性矩。
J Clin Endocrinol Metab. 2003 Dec;88(12):5778-83. doi: 10.1210/jc.2003-030201.
2
Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density.在不同骨密度增加的情况下,低密度脂蛋白受体相关蛋白5(LRP5)基因中的六个新错义突变。
Am J Hum Genet. 2003 Mar;72(3):763-71. doi: 10.1086/368277. Epub 2003 Feb 10.
3
Hyperostosis corticalis generalisata congenita.先天性全身性骨皮质增生症
J Can Assoc Radiol. 1966 Jun;17(2):67-74.
4
Van Buchem disease: surgical treatment of the mandible.范布希姆病:下颌骨的外科治疗
Ann Plast Surg. 1988 May;20(5):462-7. doi: 10.1097/00000637-198805000-00011.
5
Hyperostosis corticalis generalisata: surgical management and long-term follow-up of one patient.全身性皮质骨肥厚:1例患者的手术治疗及长期随访
Int J Oral Maxillofac Surg. 1989 Jun;18(3):155-7. doi: 10.1016/s0901-5027(89)80115-8.
6
Van Buchem disease.范布希姆病
Postgrad Med J. 1977 Aug;53(622):497-506. doi: 10.1136/pgmj.53.622.497.
7
Autosomal dominant osteosclerosis.常染色体显性遗传性骨硬化症
Radiology. 1977 Nov;125(2):547-8. doi: 10.1148/125.2.547.