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[心脏病在各类脑血管疾病中的重要性。一项前瞻性研究]

[The importance of heart disease in the various types of cerebral vascular disease. A prospective study].

作者信息

Soares Franco A, Monteiro J, Ferreira D, Fonseca T P, Melo T P, Ferro J, Freitas A, Nogueira J M, Mota E, da Costa J N

机构信息

Serviço Titulado de Medicina Interna do H.S.M., Lisboa.

出版信息

Rev Port Cardiol. 1990 May;9(5):425-32.

PMID:2206587
Abstract

UNLABELLED

A prospective study was performed in 106 patients with acute stroke. The main purpose was the cardiac evaluation in the different types of cerebrovascular disease: Intracerebral hemorrhage (H), Cortical ischaemic events (C) and Subcortical ischaemic events (SC) and also to evaluate the interest of echocardiography in detecting occult cardiac sources of emboli. The study population included 54 men and 52 women with a mean age of 66.8 +/- 10.3 years. A thorough neurologic and cardiologic study with a computed tomography of the brain (TAC) and an echocardiogram (ECO) were performed in all patients. It was found 24 (23%) of H, 40 (38%) of C and 32 (30%) of SC. In the past history, heart diseases were more prevalent in C (p less than 0.04); previous stroke and systemic hypertension (HTA) were less prevalent in H (p less than 0.008) and in C (p less than 0.004), respectively. Atrial fibrillation (FA) was more frequent in ischaemic stroke (p less than 0.02) and within these in C (p less than 0.005). No more clinical and functional cardiac features or echocardiographic aspects had any difference in their prevalence in different types of stroke. Without clinical heart disease there were 19 (18%) cases but only in 10 were found in their echocardiograms a potentially embolic heart disease (PEHD) but 8 of them had questionable pathologic significance.

IN CONCLUSION

C had more heart disease in their past history; FA is more frequent in C; it is difficult to diagnose a cerebral embolism with only a coexistent C and CPE, but if there is FA or a past history of heart disease in a C, the diagnosis of cerebral embolism is more probable; finally, echocardiography is of limited value to diagnose a PEHD in the elderly, however it makes possible to better evaluate most cardiac situations.

摘要

未标注

对106例急性中风患者进行了一项前瞻性研究。主要目的是对不同类型的脑血管疾病进行心脏评估:脑出血(H)、皮质缺血性事件(C)和皮质下缺血性事件(SC),同时评估超声心动图在检测隐匿性心脏栓子来源方面的作用。研究人群包括54名男性和52名女性,平均年龄为66.8±10.3岁。对所有患者进行了全面的神经学和心脏病学检查,包括脑部计算机断层扫描(TAC)和超声心动图(ECO)。发现脑出血患者24例(23%),皮质缺血性事件患者40例(38%),皮质下缺血性事件患者32例(30%)。在既往病史中,心脏病在皮质缺血性事件患者中更为普遍(p<0.04);既往中风和系统性高血压(HTA)在脑出血患者(p<0.008)和皮质缺血性事件患者(p<0.004)中分别较少见。心房颤动(FA)在缺血性中风中更常见(p<0.02),在皮质缺血性事件中更是如此(p<0.005)。在不同类型的中风中,其他临床和功能性心脏特征或超声心动图表现的患病率没有差异。无临床心脏病的患者有19例(18%),但超声心动图仅在10例中发现潜在的栓塞性心脏病(PEHD),其中8例的病理意义存疑。

结论

皮质缺血性事件患者既往心脏病史更多;心房颤动在皮质缺血性事件中更常见;仅存在皮质缺血性事件和可能的心脏栓子并存时,很难诊断脑栓塞,但如果皮质缺血性事件患者存在心房颤动或心脏病史,则脑栓塞的诊断可能性更大;最后,超声心动图在诊断老年人潜在的栓塞性心脏病方面价值有限,然而它有助于更好地评估大多数心脏情况。

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