Al-Ammouri Iyad, Al-Wahsh Shorouk, Khuri-Bulos Najwa
Department of Pediatrics, University of Jordan, Jordan University Hospital, Amman, Jordan.
Cardiol Young. 2012 Aug;22(4):390-5. doi: 10.1017/S1047951111001818. Epub 2011 Nov 9.
Kawasaki disease is the leading cause of acquired coronary artery disease in young children. There is a lack of data on Kawasaki disease and its effect on coronary arteries in Jordan and other developing countries. We report clinical and demographic data of Kawasaki disease in Jordan from a single institution, with emphasis on cardiac involvement and short to intermediate follow-up. Review of the medical records of 34 patients with Kawasaki disease from 1997 to 2010 was done for clinical and demographic variables. Echocardiographic and angiographic images were reviewed for patients at presentation and follow-up. The median age at presentation was 19 months, ranging from 2 months to 8 years, with a male to female ratio of 3.9:1. In all, 12 patients (35%) had incomplete Kawasaki disease. There was a high incidence of coronary artery involvement (41%), where 20.5% had aneurysms and 20.5% had ectasia without aneurysm. Most coronary aneurysms were present at the time of diagnosis. The only independent variable for prediction of coronary involvement was age, with an odds ratio of 0.63 per year (95% confidence interval 0.41-0.95).
川崎病是幼儿后天性冠状动脉疾病的主要病因。在约旦和其他发展中国家，关于川崎病及其对冠状动脉影响的数据匮乏。我们报告了来自单一机构的约旦川崎病临床和人口统计学数据，重点关注心脏受累情况以及短期至中期随访结果。对1997年至2010年期间34例川崎病患者的病历进行了临床和人口统计学变量审查。对患者就诊时和随访时的超声心动图和血管造影图像进行了复查。就诊时的中位年龄为19个月，范围从2个月至8岁，男女比例为3.9:1。共有12例患者（35%）患有不完全川崎病。冠状动脉受累发生率较高（41%），其中20.5%有动脉瘤，20.5%有扩张但无动脉瘤。大多数冠状动脉动脉瘤在诊断时就已存在。预测冠状动脉受累的唯一独立变量是年龄，每年的比值比为0.63（95%置信区间0.41 - 0.95）。
