Imaging Research, Sunnybrook Research Institute, Toronto, ON, Canada.
IEEE Trans Med Imaging. 2012 Apr;31(4):977-83. doi: 10.1109/TMI.2011.2174645. Epub 2011 Nov 4.
The introduction of electroanatomic mapping (EAM) has improved the understanding of the substrate of ventricular tachycardia. EAM systems are used to delineate scar regions responsible for the arrhythmia by creating voltage or activation time maps. Previous studies have identified the benefits of creating MR-guided voltage maps; however, in some cases voltage maps may not identify regions of slow propagation that can cause the reentrant tachycardia. In this study, we obtained local activation time maps and analyzed propagation properties by performing MR-guided mapping of the porcine left ventricle while pacing from the right ventricle. Anatomical and myocardial late gadolinium enhancement images were used for catheter navigation and identification of scar regions. Our MR-guided mapping procedure showed qualitative correspondence to conventional clinical EAM systems in healthy pigs and demonstrated altered propagation in endocardial infarct models.
电激动标测（EAM）的引入提高了对室性心动过速基质的理解。EAM 系统用于通过创建电压或激活时间图来描绘负责心律失常的瘢痕区域。先前的研究已经确定了创建磁共振引导电压图的好处；然而，在某些情况下，电压图可能无法识别可能导致折返性心动过速的缓慢传播区域。在这项研究中，我们通过从右心室起搏获得局部激活时间图，并分析了通过在猪左心室进行磁共振引导标测的传播特性。解剖学和心肌晚期钆增强图像用于导管导航和瘢痕区域的识别。我们的磁共振引导标测程序在健康猪中与传统的临床 EAM 系统具有定性对应关系，并在心内膜下梗死模型中显示了传播的改变。
