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儿科急诊科就诊的青春期男性性传播感染的评估与管理:主诉具有诊断价值吗?

Evaluation and management of sexually transmitted infections in adolescent males presenting to a pediatric emergency department: is the chief complaint diagnostic?

作者信息

Timm Nathan, Bouvay Kamali, Scheid Beth, Defoor W Robert

机构信息

Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

出版信息

Pediatr Emerg Care. 2011 Nov;27(11):1042-4. doi: 10.1097/PEC.0b013e318235e950.

Abstract

OBJECTIVES

The objectives of the study were to (1) describe evaluation and treatment patterns for adolescent males presenting with a concern for sexually transmitted infection (STI) in a pediatric emergency department, (2) assess the rates of STIs in symptomatic males, and (3) determine the utility of urinalysis alone in predicting STIs in adolescent males.

METHODS

A retrospective cohort study was conducted of all patients presenting to our pediatric emergency department from January 1, 2007, to December 31, 2007. Inclusion criteria included males, aged 15 to 21 years, with an STI or urinary chief complaint. Exclusion criteria were referrals from pediatricians, a previous history of urinary tract infection or preexisting urologic condition, or primary complaint of scrotal and/or testicular pain.

RESULTS

A total of 270 patients were identified. Testing included urinalysis with microscopy (UA) (64%), urine culture (53%), Neisseria gonorrhoeae (GC), and Chlamydia trachomatis (CT) (93%), and Trichomonas vaginalis (5%). Sixty-four percent of males tested positive for either GC or CT, or both. Overall, 91% of patients were treated for CT and GC, 18% for T. vaginalis, and 5% for urinary tract infection. The sensitivity and specificity of a positive UA for presence of GC and/or CT were 86% and 82%, respectively, whereas the positive and negative predictive values were 89% and 77%, respectively. There were no positive urine cultures in the cohort.

CONCLUSIONS

Sixty-four percent of patients were diagnosed with either GC or CT. Although UA is helpful in predicting STI, limited use is warranted, given the high prevalence of disease in this selected population. The urine culture does not appear to be a necessary adjunct in the management of these patients.

摘要

目的

本研究的目的是:(1)描述儿科急诊科中因担心性传播感染(STI)前来就诊的青春期男性的评估和治疗模式;(2)评估有症状男性的性传播感染率;(3)确定仅通过尿液分析预测青春期男性性传播感染的效用。

方法

对2007年1月1日至2007年12月31日期间到我们儿科急诊科就诊的所有患者进行了一项回顾性队列研究。纳入标准包括年龄在15至21岁之间、患有性传播感染或有泌尿系统主诉的男性。排除标准为儿科医生的转诊、既往尿路感染病史或已存在的泌尿系统疾病,或阴囊和/或睾丸疼痛的主要主诉。

结果

共确定了270名患者。检测包括显微镜下尿液分析(UA)(64%)、尿培养(53%)、淋病奈瑟菌(GC)和沙眼衣原体(CT)(93%)以及阴道毛滴虫(5%)。64%的男性GC或CT检测呈阳性,或两者均呈阳性。总体而言,91%的患者接受了CT和GC治疗,18%接受了阴道毛滴虫治疗,5%接受了尿路感染治疗。UA阳性对GC和/或CT存在的敏感性和特异性分别为86%和82%,而阳性和阴性预测值分别为89%和77%。该队列中尿培养均为阴性。

结论

64%的患者被诊断患有GC或CT。虽然尿液分析有助于预测性传播感染,但鉴于该特定人群中疾病的高患病率,应谨慎使用。尿培养似乎不是这些患者管理中的必要辅助检查。

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