Fasheh Youssef Wael, Pino Ramírez Rosa, Campistol Plana Jaume, Pineda Marfa Mercedes
Pediatrics Service, University Hospital Sant Joan de Déu and Centre for Biomedical Network Research on Rare Diseases, Barcelona, Spain.
Pediatr Emerg Care. 2011 Nov;27(11):1062-4. doi: 10.1097/PEC.0b013e31823b45b3.
Since the description of afebrile convulsions in the course of mild acute gastroenteritis (AGE) in 1982 by Morooka in Japan, there have been few reports of further cases outside Asia. The aim of this study was to share our casuistry--from a non-Asian country.
This is a retrospective study of identified cases in our center from January 2002 to December 2007.
A total of 28 patients were studied. All were previously healthy patients who experienced convulsions with mild AGE without dehydration and with normal blood analysis. The mean age was 17.25 months (range, 6-48 months), with 93% younger than 24 months. Seizures were generalized tonic-clonic (61%), followed by generalized tonic (31%), and hypotonic (5.2%), with 2 (2.6%) partial. Only 8 patients (28.6%) presented one convulsion, and in 13 patients (46%), the seizures were in clusters from 3 to 6. Eleven patients (39%) presented 2 different types of convulsion. The duration of the crises ranged from 30 seconds to 10 minutes, and all of them occurred within 24 hours of the first. Electroencephalograms, obtained for all patients, were normal. Rotavirus was the main infectious agent in the AGEs, found in 11 patients with 22 determinations. In one patient, Salmonella serotype Enteritidis was isolated. All of the patients developed favorably, with no sequelae or epilepsy during the follow-up period.
Afebrile convulsion in the course of mild gastroenteritis exists in our environment. It is a banal symptom in the course of the disease with good prognosis. Recognition of this fact may help avoid needless explorations and treatment in patients of this kind.
自1982年日本的室冈描述了轻度急性胃肠炎（AGE）病程中的无热惊厥以来，亚洲以外地区鲜有更多病例报告。本研究的目的是分享我们来自一个非亚洲国家的病例情况。
这是一项对2002年1月至2007年12月在我们中心确诊病例的回顾性研究。
共研究了28例患者。所有患者此前均健康，在患轻度AGE时出现惊厥，无脱水且血液分析正常。平均年龄为17.25个月（范围6 - 48个月），93%的患者年龄小于24个月。惊厥类型为全身性强直阵挛性发作（61%），其次是全身性强直性发作（31%）和低张性发作（5.2%），2例（2.6%）为部分性发作。仅8例患者（28.6%）发作1次惊厥，13例患者（46%）惊厥呈3至6次成串发作。11例患者（39%）出现2种不同类型的惊厥。发作持续时间为30秒至1分钟，均在首次发作后24小时内发生。所有患者的脑电图均正常。轮状病毒是AGE中的主要感染源，在11例患者的22次检测中被发现。1例患者分离出肠炎沙门氏菌血清型。所有患者病情转归良好，随访期间无后遗症或癫痫发作。
在我们的环境中存在轻度胃肠炎病程中的无热惊厥。这是该疾病过程中的一个常见症状，预后良好。认识到这一事实可能有助于避免对此类患者进行不必要的检查和治疗。
