血栓性血小板减少性紫癜

Thrombotic thrombocytopenic purpura.

作者信息

Koyfman Alex, Brém Elizabeth, Chiang Vincent W

机构信息

Department of Emergency Medicine, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, MA 02115, USA.

出版信息

Pediatr Emerg Care. 2011 Nov;27(11):1085-8; quiz 1089-90. doi: 10.1097/PEC.0b013e318236068c.

DOI:10.1097/PEC.0b013e318236068c

PMID:22068077

Abstract

In 1924, Dr Eli Moschcowitz described a 16-year-old adolescent girl with abrupt onset of petechiae, hemolytic anemia, followed by paralysis, coma, and death. Autopsy showed widespread hyaline thrombi in the terminal arterioles and capillaries of various organs. The syndrome described by Moschowitz is now known as thrombotic thrombocytopenic purpura.

摘要

1924年，伊莱·莫肖科维茨医生描述了一名16岁少女，她突然出现瘀点、溶血性贫血，随后出现瘫痪、昏迷并死亡。尸检显示，多个器官的终末小动脉和毛细血管中存在广泛的透明血栓。莫肖科维茨所描述的综合征现在被称为血栓性血小板减少性紫癜。