Passouant P, Besset A, Billiard M, Negre C
Rev Electroencephalogr Neurophysiol Clin. 1978 Sep;8(3):326-34. doi: 10.1016/s0370-4475(78)80008-2.
Piribedil, a dopamine agonist, was administered to 5 normal male subjects for two weeks. During the first two nights there was a reduction of about 17 p. 100 in paradoxical sleep (PS) and an increase of about 13 p. 100 in slow sleep II. There was a 15 p. 100 increase in PS during the third night. This increase is maintained for 8 nights in 3 subjects and 13 nights in 2 subjects. Other sleep parameters were not altered. Piribedil appears to give the impression of satisfactory sleep by reducing the subjective period before falling asleep. Piribedil also diminishes the remembrance of dreams.
将多巴胺激动剂吡贝地尔给予5名正常男性受试者，为期两周。在头两个晚上，异相睡眠（PS）减少了约17%，慢波睡眠II增加了约13%。在第三个晚上，PS增加了15%。这种增加在3名受试者中持续了8个晚上，在2名受试者中持续了13个晚上。其他睡眠参数未改变。吡贝地尔似乎通过缩短入睡的主观时间，给人以睡眠良好的印象。吡贝地尔还减少了对梦的记忆。
