Cardiology Division, Department of Medicine, Columbia University Medical Center/New York-Presbyterian Hospital, 622 West 168th Street PH 10-203A, New York, NY 10032, USA.
J Nucl Cardiol. 2012 Feb;19(1):100-8. doi: 10.1007/s12350-011-9473-x. Epub 2011 Nov 9.
Coronary computed tomographic angiography (CCTA) is associated with high radiation dose to the female breasts. Bismuth breast shielding offers the potential to significantly reduce dose to the breasts and nearby organs, but the magnitude of this reduction and its impact on image quality and radiation dose have not been evaluated.
Radiation doses from CCTA to critical organs were determined using metal-oxide-semiconductor field-effect transistors positioned in a customized anthropomorphic whole-body dosimetry verification phantom. Image noise and signal were measured in regions of interest (ROIs) including the coronary arteries.
With bismuth shielding, breast radiation dose was reduced 46%-57% depending on breast size and scanning technique, with more moderate dose reduction to the heart, lungs, and esophagus. However, shielding significantly decreased image signal (by 14.6 HU) and contrast (by 28.4 HU), modestly but significantly increased image noise in ROIs in locations of coronary arteries, and decreased contrast-to-noise ratio by 20.9%.
While bismuth breast shielding can significantly decrease radiation dose to critical organs, it is associated with an increase in image noise, decrease in contrast-to-noise, and changes tissue attenuation characteristics in the location of the coronary arteries.
冠状动脉计算机断层扫描血管造影术(CCTA)会对女性乳房造成较高的辐射剂量。使用铋屏蔽乳房技术可以显著降低乳房和附近器官的剂量,但这种降低的幅度以及对图像质量和辐射剂量的影响尚未得到评估。
通过在定制的人体全身剂量验证体模中放置金属氧化物半导体场效应晶体管,确定 CCTA 对关键器官的辐射剂量。在包括冠状动脉在内的感兴趣区域(ROI)中测量图像噪声和信号。
使用铋屏蔽,乳房的辐射剂量降低了 46%-57%,具体取决于乳房的大小和扫描技术,对心脏、肺部和食管的剂量降低程度较为适中。然而,屏蔽显著降低了图像信号(降低了 14.6 HU)和对比度(降低了 28.4 HU),在冠状动脉位置的 ROI 中适度但显著增加了图像噪声,并降低了 20.9%的对比噪声比。
虽然铋屏蔽乳房技术可以显著降低关键器官的辐射剂量,但它会导致图像噪声增加、对比噪声降低以及冠状动脉部位的组织衰减特性发生变化。