Marjanović Ivan, Mijajlović Milija, Covicković-Sternić Nadezda, Kontić Djordje, Hentova-Senćanić Paraskeva, Marković Vujica, Bozić Marija
Clinic of Eye Diseases, Clinical Centre of Serbia, Belgrade, Serbia.
Srp Arh Celok Lek. 2011 Sep-Oct;139(9-10):572-8.
An altered perfusion of the optic nerve head has been proposed as a pathogenic factor in glaucoma.
The aim of this study was to evaluate the correlation between ocular pulse amplitude (OPA), measured by Dynamic contour tonometer (DCT) and colour Doppler imaging (CDI) of the arteric retrobulbar vessels.
Twenty patients older than 50 years were examined, and divided into two equal groups. The first group comprised of patients with normal tension glaucoma treated with topical antiglaucomatous therapy, and the second group included patients with ocular hypertension and glaucoma suspicious without any antiglaucomatous therapy. Ocular pulse amplitude (OPA) was measured with DCT. CDI was also performed. We measured haemodynamic parameters of the internal carotid artery (ICA), ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary arteries (PCA). Peak systolic (PSV), end-diastolic (EDV) velocities were measured, and resistance index (RI) and pulsatility index (PI) were calculated.
Correlation with OPA showed indirect servitude in the RI of the ICA, RI and PI of the CRA, in the first group; and in the PSV and EDV of the ICA, in the RI and PI of the OA, EDV and RI of the CRA, and RI of the PCA, in the second group
Increase of OPA was mostly followed by the increase of the parameters (PSV, EDV, RI, and PI) of the arteric retrobulbar vessels in the first group; in the second group, increase of OPA was in almost 50% of parameters followed by their decrease.
视神经乳头灌注改变被认为是青光眼的致病因素。
本研究旨在评估动态轮廓眼压计（DCT）测量的眼动脉搏动幅度（OPA）与球后动脉彩色多普勒成像（CDI）之间的相关性。
对20例年龄大于50岁的患者进行检查，并将其分为两组，每组人数相等。第一组包括接受局部抗青光眼治疗的正常眼压性青光眼患者，第二组包括未经任何抗青光眼治疗的高眼压症和可疑青光眼患者。用DCT测量眼动脉搏动幅度（OPA），同时进行CDI检查。我们测量了颈内动脉（ICA）、眼动脉（OA）、视网膜中央动脉（CRA）和睫状后动脉（PCA）的血流动力学参数。测量收缩期峰值（PSV）、舒张末期（EDV）速度，并计算阻力指数（RI）和搏动指数（PI）。
第一组中，OPA与ICA的RI、CRA的RI和PI呈间接相关性；第二组中，OPA与ICA的PSV和EDV、OA的RI和PI、CRA的EDV和RI以及PCA的RI呈相关性。
第一组中，OPA增加大多伴随着球后动脉参数（PSV、EDV、RI和PI）的增加；第二组中，OPA增加后，近50%的参数反而下降。
