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鞘内注射芬太尼的小剂量重比重布比卡因腰麻用于宫腔镜手术:一项病例系列研究。

Low-dose spinal anesthesia with hyperbaric bupivacaine with intrathecal fentanyl for operative hysteroscopy: a case series study.

机构信息

Department of Pediatrics, Obstetrics and Reproductive Medicine, Section of Obstetrics and Gynecology, University of Siena, Siena, Italy.

出版信息

J Minim Invasive Gynecol. 2012 Jan-Feb;19(1):107-12. doi: 10.1016/j.jmig.2011.08.728. Epub 2011 Nov 9.

Abstract

STUDY OBJECTIVE

To estimate the efficacy and tolerability of low dose spinal anesthesia during operative hysteroscopy in a group of patients with high surgical risks.

DESIGN

Case series study (Canadian Task Force Classification II-2).

SETTING

Tertiary centers for women health care.

PATIENTS

A total of 47 women affected by endometrial polyps (n = 32), myomas (n = 8), and abnormal uterine bleeding (n = 7) scheduled for inpatient operative hysteroscopy.

INTERVENTIONS

Transvaginal ultrasonography; office diagnostic hysteroscopy; preoperative evaluation of American Society of Anesthesiologist (ASA) classification; inpatient operative hysteroscopy; low-dose spinal anesthesia with hyperbaric bupivacaine; compilation of a questionnaire.

MAIN OUTCOME MEASURES

Practicability and patients' subjective experiences with spinal anesthesia; duration of cervical dilation and for operative hysteroscopy; infusion volume needed; incidence of surgical complications.

RESULTS

Resectoscopy was performed in all patients, with the exception of 1 woman (2.1%) in which spinal anesthesia was unsuccessful. No statistically significant differences were noted among groups in terms of intra- and peri-operative findings. Sensory block induced by spinal anesthesia was suitable for surgery in all patients, and side effects occurred far less frequently than mentioned in the literature. Data reported in the questionnaire revealed that 93.5% of women would choose a spinal anesthesia again for a potential operative hysteroscopy in the future, since for 89.1% of them long lasting anesthesia is of relevance.

CONCLUSIONS

Low-dose spinal anesthesia is a feasible technique in the inpatient setting for operative hysteroscopy in women with high surgical risks.

摘要

研究目的

评估高手术风险患者行宫腔镜手术时应用小剂量椎管内麻醉的疗效和耐受性。

设计

病例系列研究(加拿大分级 II-2)。

地点

妇女保健三级中心。

患者

共 47 例因子宫内膜息肉(n=32)、肌瘤(n=8)和异常子宫出血(n=7)接受住院宫腔镜手术的患者。

干预措施

经阴道超声检查;门诊诊断性宫腔镜检查;美国麻醉医师协会(ASA)分级术前评估;住院宫腔镜手术;应用布比卡因重比重液行小剂量椎管内麻醉;问卷调查。

主要观察指标

椎管内麻醉的可行性和患者的主观感受;宫颈扩张和宫腔镜手术时间;所需输液量;手术并发症发生率。

结果

所有患者均行宫腔镜切除术,除 1 例(2.1%)患者因椎管内麻醉失败未行切除术。各组间术中及围术期发现无统计学差异。脊髓麻醉引起的感觉阻滞适合所有患者手术,且副作用的发生频率远低于文献报道。问卷调查数据显示,93.5%的女性将来愿意再次选择椎管内麻醉行潜在的宫腔镜手术,因为对 89.1%的女性来说,长时间麻醉很重要。

结论

对于高手术风险的宫腔镜手术患者,小剂量椎管内麻醉在住院环境下是一种可行的技术。

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