Agamenon Magalhães Hospital, Pernambuco University, Recife-PE Brazil.
J Clin Densitom. 2012 Jan-Mar;15(1):55-60. doi: 10.1016/j.jocd.2011.07.002. Epub 2011 Nov 9.
Atherosclerotic vascular disease is common in diabetes, and some data support a link with bone loss. This study evaluates the association between osteoporosis and clinical and metabolic factors and chronic complications of diabetes. We studied 59 diabetic men aged 50-80 yr who were assessed with bone densitometry (dual-energy X-ray absorptiometry). Of them, 10.2% of the patients were found to have osteoporosis in the lumbar spine and 45.8% osteopenia, whereas in the femoral neck, 11.8% had osteoporosis and 49% had osteopenia. There was a significant association of osteoporosis in the lumbar spine L1-L4 (p=0.004) and in the femoral neck (p=0.036) with iliac artery calcification. In addition, there was no association with any other metabolic factors, clinical factors, or chronic complications of diabetes evaluated, except for an association between a previous personal history of fractures (p=0.016) and low bone mineral density in the femoral neck. In conclusion, we found a positive association between the iliac artery calcification and osteoporosis in type 2 diabetic male patients.
动脉粥样硬化性血管疾病在糖尿病中很常见，一些数据支持其与骨丢失之间存在关联。本研究评估了骨质疏松症与糖尿病的临床和代谢因素及慢性并发症之间的关系。我们研究了 59 名年龄在 50-80 岁的男性 2 型糖尿病患者，他们接受了骨密度（双能 X 射线吸收法）检测。其中，10.2%的患者腰椎骨密度降低，45.8%为骨量减少，而在股骨颈，11.8%的患者骨质疏松，49%为骨量减少。腰椎 L1-L4 （p=0.004）和股骨颈（p=0.036）的骨质疏松与髂动脉钙化有显著相关性。此外，除了既往个人骨折史（p=0.016）与股骨颈骨密度降低之间存在相关性外，与评估的任何其他代谢因素、临床因素或糖尿病慢性并发症均无相关性。总之，我们发现 2 型糖尿病男性患者的髂动脉钙化与骨质疏松之间存在正相关。
