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2
Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women.相对低碳水化合物、热量限制饮食的临床经验可改善超重、胰岛素抵抗的南亚印度女性的胰岛素敏感性及相关代谢异常。
Asia Pac J Clin Nutr. 2008;17(4):669-71.
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Obesity Reduction Black Intervention Trial (ORBIT): design and baseline characteristics.肥胖减少黑色干预试验（ORBIT）：设计与基线特征
J Womens Health (Larchmt). 2008 Sep;17(7):1099-110. doi: 10.1089/jwh.2007.0614.
4
Gentle exercise of 40 minutes with dietary counseling is effective in treating metabolic syndrome.
Tohoku J Exp Med. 2008 Aug;215(4):355-61. doi: 10.1620/tjem.215.355.
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How useful is waist circumference for assessment of abdominal obesity in Korean pre-menopausal women during weight loss?腰围对于评估韩国绝经前女性减肥期间的腹部肥胖情况有多大用处？
Asia Pac J Clin Nutr. 2008;17(2):229-34.
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HDL-cholesterol modulation and its impact on the management of cardiovascular risk.高密度脂蛋白胆固醇调节及其对心血管风险管理的影响。
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7
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Clinical inquiries. How do exercise and diet compare for weight loss?
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[随机对照试验：饮食与运动在代谢综合征女性中的作用]

[Randomised controlled trial: the role of diet and exercise in women with metabolic syndrome].

作者信息

Miguel Soca Pedro Enrique, Peña Pérez Idania, Niño Escofet Silvio, Cruz Torres Walter, Niño Peña Aluett, Ponce De León Delmis

机构信息

Universidad Médica Mariana Grajales Coello, Holguín, Cuba.

出版信息

Aten Primaria. 2012 Jul;44(7):387-93. doi: 10.1016/j.aprim.2011.07.010. Epub 2011 Nov 8.

DOI:10.1016/j.aprim.2011.07.010
PMID:22071199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7025924/
Abstract

OBJECTIVE

To evaluate a program of nutritional recommendations and exercise in women with metabolic syndrome.

DESIGN

Multicentre randomised controlled trial.

LOCATION

Primary Health Care, Holguin, Cuba.

PARTICIPANTS

A cluster sample of 150 obese women with metabolic syndrome without glucose disturbances, were randomly assigned to a control (n=70) or experimental (n=80) group. A total of 62 women in the control group and 60 in the intervention group completed the study (June 2008-July 2009).

INTERVENTIONS

Low calorie diets and a program of exercises in the experimental group. Usual care in the control group.

MEASUREMENTS

Body weight, body mass index, waist circumference, blood pressure, blood glucose and lipid profile.

RESULTS

Compared to the control group, after one year, the experimental group had a lower, diastolic blood pressure (78±0.9 vs 91±1.1mm Hg), total cholesterol (4.7±0.1 vs 6.0 ±0.1mmol/L), triglycerides (1.9±0.0 vs 2.9±0.1mmol/L) and LDL cholesterol (2.5±0.0 vs 3.5±0.1mmol/L), and a higher HDL-cholesterol (1.2±0.0 vs 1.1±0.0mmol/L). There were no appreciable changes in weight, body mass index, waist circumference, systolic blood pressure and blood glucose.

CONCLUSIONS

We demonstrated the effectiveness of the intervention program on blood pressure and blood lipid profile.

摘要

目的

评估一项针对患有代谢综合征女性的营养建议和运动计划。

设计

多中心随机对照试验。

地点

古巴奥尔金市的初级卫生保健机构。

参与者

选取150名患有代谢综合征且无血糖紊乱的肥胖女性作为整群样本，随机分为对照组（n = 70）和试验组（n = 80）。对照组共有62名女性，干预组有60名女性完成了研究（2008年6月至2009年7月）。

干预措施

试验组采用低热量饮食和运动计划。对照组采用常规护理。

测量指标

体重、体重指数、腰围、血压、血糖和血脂谱。

结果

与对照组相比，一年后试验组的舒张压较低（78±0.9 vs 91±1.1mmHg），总胆固醇较低（4.7±0.1 vs 6.0±0.1mmol/L），甘油三酯较低（1.9±0.0 vs 2.9±0.1mmol/L），低密度脂蛋白胆固醇较低（2.5±0.0 vs 3.5±0.1mmol/L），高密度脂蛋白胆固醇较高（1.2±0.0 vs 1.1±0.0mmol/L）。体重、体重指数、腰围、收缩压和血糖没有明显变化。

结论

我们证明了干预计划对血压和血脂谱的有效性。