[通过确定施加除颤脉冲的正确时间显著降低除颤电流的可能性。一个数学模型]

[A possibility of significant lowering the defibrillation current by determining the right time for application of a defibrillating pulse. A mathematical model].

作者信息

Pertsov A M, Biktashev V N, Ermakova E A, Krinskiĭ V I

出版信息

Biofizika. 1990 May-Jun;35(3):500-3.

PMID:2207196

Abstract

The effect of defibrillating pulses on the functionally determined re-entries (leading circles) was studied by computer simulation. Arrhythmias caused by different numbers of leading circles (from 1 to 18) were investigated. The defibrillation threshold was found to vary 2-4-fold, depending on the time of application of a pulse. At small currents the defibrillation mechanism is principally different from the commonly known one and is linked to the movement of leading circles towards each other or towards the boundary of the excitable tissue.

摘要

通过计算机模拟研究了除颤脉冲对功能确定的折返（主导环）的影响。研究了由不同数量的主导环（从1到18个）引起的心律失常。发现除颤阈值变化2至4倍，这取决于脉冲施加的时间。在小电流情况下，除颤机制与常见机制主要不同，并且与主导环相互靠近或向可兴奋组织边界移动有关。