Kogure K, Scheinberg P, Kishikawa H, Utsunomiya Y, Busto R
Stroke. 1979 Mar-Apr;10(2):179-84. doi: 10.1161/01.str.10.2.179.
Studies in rats were designed to separate and define the roles of the intrinsic and extrinsic adrenergic neurons in the control of cerebral blood flow (CBF) and cerebral energy metabolism. The data suggest several conclusions: 1. Arterial sympathetic innervation plays a role in the autoregulation of cerebral circulation. 2. The central adrenergic neurons have several functions: a) they enhance cerebral vascular tone by action on alpha receptor sites. b) They play an important role in the metabolic control of CBF. The proton-sensitive receptor sites on blood vessel walls require beta-adrenergic input in order to function. c) They influence metabolic rate of brain tissue by acting on beta-receptor sites on the cell membrane.
对大鼠的研究旨在区分并明确内在和外在肾上腺素能神经元在控制脑血流量（CBF）和脑能量代谢中的作用。数据表明了几个结论：1. 动脉交感神经支配在脑循环的自动调节中起作用。2. 中枢肾上腺素能神经元有多种功能：a）它们通过作用于α受体位点增强脑血管张力。b）它们在CBF的代谢控制中起重要作用。血管壁上的质子敏感受体位点需要β肾上腺素能输入才能发挥作用。c）它们通过作用于细胞膜上的β受体位点影响脑组织的代谢率。
