Department of Clinical Science, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.
Vet Comp Oncol. 2011 Dec;9(4):304-9. doi: 10.1111/j.1476-5829.2011.00278.x. Epub 2011 Jul 26.
This case series describes a rare entity, nasal angiofibroma, in 13 dogs that were presented to the University of Wisconsin, School of Veterinary Medicine from 1988 to 2000. All dogs in this case series presented with clinical signs and radiographic changes that were strongly suggestive of a locally invasive neoplasm. However, histopathology completed on transnostral core biopsy samples revealed benign appearing vascular proliferation with secondary lymphosuppurative inflammation was established despite cytologic criteria of malignancy present in five dogs. On the basis of the outcomes in this case series, nasal angiofibroma should be considered a differential for dogs presenting with clinical signs consistent with a malignant nasal tumour.
本病例系列描述了 13 只犬的一种罕见疾病,即鼻腔血管纤维瘤,这些犬于 1988 年至 2000 年期间到威斯康星大学兽医学院就诊。本病例系列中的所有犬均表现出强烈提示局部侵袭性肿瘤的临床症状和影像学改变。然而,经鼻腔经颅芯活检样本的组织病理学检查显示,尽管有 5 只犬存在细胞学恶性标准,但良性表现的血管增生伴继发性淋巴浆细胞炎症。基于本病例系列的结果,对于出现与恶性鼻腔肿瘤一致的临床症状的犬,应考虑鼻腔血管纤维瘤作为鉴别诊断。