Rogers K S, Walker M A, Helman R G
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843, USA.
J Am Anim Hosp Assoc. 1996 Mar-Apr;32(2):103-10. doi: 10.5326/15473317-32-2-103.
Squamous cell carcinoma of the canine nasal cavity and frontal sinus was diagnosed in eight cases between May 1988 and April 1994. The most common presenting complaints were nasal discharge, including epistaxis; sneezing; and facial deformity or exophthalmos. Metastasis was not identified in any case, but bone lysis and invasion into tissues outside the nasal cavity were noted in five cases. Computed tomograms were performed in five cases and were more useful than radiographs in determining the extent of neoplastic involvement. Euthanasia was performed within one week of diagnosis in three cases at the owner's request; one case died at home within one month; and the remaining four cases were euthanized within eight months due to progressive clinical signs. The mean survival time in these eight cases was three months, with a range of zero weeks to eight months.
1988年5月至1994年4月期间，8例犬鼻腔和额窦鳞状细胞癌被确诊。最常见的主诉症状为鼻分泌物增多，包括鼻出血；打喷嚏；以及面部畸形或眼球突出。所有病例均未发现转移，但5例出现骨溶解和鼻腔外组织浸润。5例进行了计算机断层扫描，在确定肿瘤累及范围方面，计算机断层扫描比X光片更有用。3例应主人要求在诊断后一周内实施安乐死；1例在一个月内死于家中；其余4例因临床症状进展在8个月内实施安乐死。这8例的平均生存时间为3个月，范围为0周零天至8个月。
