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开腹胆囊切除术的胸段硬膜外麻醉

Thoracic epidural anaesthesia for open cholecystectomy.

作者信息

Zahoor Muhammad Umar, Masroor Rehan, Khurshid Tassadaq, Azhar Raheel, Amjad Yasin Malik Muhammad

机构信息

Department of Anaesthesia and Intensive Care, Combined Military Hospital (CMH), Skardu.

出版信息

J Coll Physicians Surg Pak. 2011 Nov;21(11):654-8.

PMID:22078342
Abstract

OBJECTIVE

To compare the postoperative pain relief and vomiting and the length of hospital stay in patients undergoing open cholecystectomy under general anaesthesia versus those receiving thoracic epidural anaesthesia.

STUDY DESIGN

Quasi experimental study.

PLACE AND DURATION OF STUDY

The Combined Military Hospital, Skardu, from February 2009 to July 2010.

METHODOLOGY

American Society of Anaesthesiology (ASA) physical status (PS) I and II patients of either gender undergoing un-complicated open cholecystectomy were randomly divided into two groups, group 1 (n=51) received general anaesthesia (GA) and group 2 (n=49) received thoracic epidural anaesthesia (EA). Patients of both the groups were assessed for postoperative pain, vomiting and length of hospital stay. Chi-square test was applied to compare the two groups and obtain the p-value. P-value of less than 0.05 was considered significant.

RESULTS

Thirty six patients of GA group did not require additional analgesics for postoperative pain relief; however, injection Ketorolac had to be administered to 15 patients (29.4%) for pain relief in the postoperative period. Two patients (4.1%) in the EA group required additional analgesic during that period. Eleven patients (21.5%) in the GA group had postoperative vomiting. In the EA group only 1 patient (2%) had postoperative vomiting. Patients in EA group had better postoperative pain relief (p = 0.001) and remained free from vomiting than the GA group (p = 0.003). Thirty six patients (70.5%) of the GA group and 34 patients (69.4%) in the EA group were discharged within 36 hours postoperatively (p = 0.896).

CONCLUSION

The use of intra-operative epidural anaesthesia combined with postoperative epidural analgesia was found to be associated with reduction in the postoperative pain and vomiting in patients undergoing open cholecystectomy.

摘要

目的

比较全身麻醉下接受开腹胆囊切除术的患者与接受胸段硬膜外麻醉的患者术后疼痛缓解情况、呕吐情况及住院时间。

研究设计

半实验性研究。

研究地点及时间

2009年2月至2010年7月,斯卡都联合军事医院。

方法

将接受非复杂性开腹胆囊切除术的美国麻醉医师协会(ASA)身体状况(PS)I级和II级的患者随机分为两组,第1组(n = 51)接受全身麻醉(GA),第2组(n = 49)接受胸段硬膜外麻醉(EA)。对两组患者的术后疼痛、呕吐及住院时间进行评估。应用卡方检验比较两组并得出p值。p值小于0.05被认为具有统计学意义。

结果

GA组36例患者术后疼痛缓解无需额外使用镇痛药;然而,术后有15例患者(29.4%)需注射酮咯酸以缓解疼痛。EA组在此期间有2例患者(4.1%)需额外使用镇痛药。GA组有11例患者(21.5%)术后出现呕吐。EA组仅有1例患者(2%)术后出现呕吐。EA组患者术后疼痛缓解情况更好(p = 0.001),且比GA组更少出现呕吐(p = 0.003)。GA组36例患者(70.5%)和EA组34例患者(69.4%)术后36小时内出院(p = 0.896)。

结论

研究发现,术中硬膜外麻醉联合术后硬膜外镇痛可减少开腹胆囊切除术患者的术后疼痛和呕吐。

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