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阵发性室上性心动过速病史患者心房颤动的患病率。

Prevalence of atrial fibrillation in patients with history of paroxysmal supraventricular tachycardia.

机构信息

Department of cardiology, University Hospital of Brabois, Vandoeuvre, France.

出版信息

Int J Cardiol. 2013 Jun 5;166(1):221-4. doi: 10.1016/j.ijcard.2011.10.091. Epub 2011 Nov 10.

Abstract

OBJECTIVES

This study was performed to evaluate the prevalence of atrial fibrillation (AF) in patients seen for paroxysmal supraventricular tachycardia (PSVT) and to identify factors favoring AF. AF incidence is increased in patients with PSVT, but AF risk factors are unknown.

POPULATION

1187 patients, mean age 50 ± 19 years, were consecutively studied for spontaneous PSVT confirmed by electrophysiological study (EPS). Patients with anterograde conduction through an accessory pathway were excluded.

METHODS

Clinical factors, age, gender, heart disease (HD) and electrophysiological data were noted. Patients with and without AF were compared. Mean follow-up was 4.48 ± 4.9 years.

RESULTS

61 patients developed documented paroxysmal or permanent AF or atrial flutter (5%). They were older than patients without AF (59 vs 49 years, p<0.0005), were more frequently men (59% vs 37%) (p<0.002), had more frequently prior AF (24.5% vs 0.5%) (p<0.0001) and associated HD (18% vs 5%) (p<0.004). There were no differences at EPS concerning the mechanism of re-entry. AF induction or occurrence during EPS was more frequent in patients with AF (31%) than in patients without AF (9%) (p<0.001). Multivariate analysis showed age, male gender, prior AF, HD and atrial vulnerability during EPS were independent predictors of AF. Univariate comparison between both groups suggests no effect of PSVT ablation on the incidence of AF.

CONCLUSIONS

The prevalence of AF in our population was only 5%. The risk of AF was correlated with the classical risk factors of AF and atrial vulnerability during electrophysiological study. Patients with these risk factors should be followed.

摘要

目的

本研究旨在评估阵发性室上性心动过速(PSVT)患者中房颤(AF)的患病率,并确定有利于 AF 的因素。AF 在 PSVT 患者中发病率增加,但 AF 的危险因素尚不清楚。

人群

连续研究了 1187 名年龄在 50 ± 19 岁的自发性 PSVT 患者,这些患者通过电生理研究(EPS)证实。排除了前传通过附加途径的患者。

方法

记录临床因素、年龄、性别、心脏病(HD)和电生理数据。比较有和无 AF 的患者。平均随访时间为 4.48 ± 4.9 年。

结果

61 名患者出现了记录在案的阵发性或永久性 AF 或房扑(5%)。他们比没有 AF 的患者年龄更大(59 岁 vs 49 岁,p<0.0005),更常为男性(59% vs 37%)(p<0.002),更常患有既往 AF(24.5% vs 0.5%)(p<0.0001)和相关的 HD(18% vs 5%)(p<0.004)。在 EPS 中,折返机制没有差异。AF 诱导或在 EPS 中发生的患者在有 AF 的患者中更为常见(31%),而在没有 AF 的患者中为 9%(p<0.001)。多变量分析显示,年龄、男性、既往 AF、HD 和 EPS 期间的心房易损性是 AF 的独立预测因素。两组间的单变量比较表明,PSVT 消融对 AF 发生率没有影响。

结论

我们人群中 AF 的患病率仅为 5%。AF 的风险与 AF 的经典危险因素和电生理研究期间的心房易损性相关。具有这些危险因素的患者应进行随访。

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