Department of Otolaryngology, Faculty of Medicine, Kagawa University, Japan.
Int J Oral Maxillofac Surg. 2012 Apr;41(4):444-7. doi: 10.1016/j.ijom.2011.10.013. Epub 2011 Nov 10.
Basal cell adenocarcinoma (BCAC) is a rare malignant neoplasm in the salivary glands and BCAC of the minor salivary glands is exceedingly rare. Only nine cases of palatal BCACs of the minor salivary gland have been reported. BCAC is a low-grade malignant tumour which shares many histologic characteristics with basal cell adenoma. Histological differentiation between the two is difficult and they are often discriminated only by invasion of local structures or by perineural or vascular invasive figures. The authors describe the case of a 69-year-old man with a massive BCAC of a palatal minor salivary gland that progressed into the nasal cavity and pterygopalatine fossa and was treated by a subtotal maxillectomy. This is a highly locally advanced case which required a wider surgical excision range than other previously reported BCAC cases of the palatal minor salivary glands. In this case, the proper diagnosis could not be made by local biopsy alone. It should be kept in mind that it may be difficult to distinguish BCAC from basal cell adenoma by microscopic examination of biopsy specimens alone.
基底细胞腺癌（BCAC）是一种罕见的唾液腺恶性肿瘤，而小唾液腺的 BCAC 则极为罕见。仅有 9 例发生于小唾液腺的腭部 BCAC 被报道。BCAC 是一种低度恶性肿瘤，其具有许多与基底细胞腺瘤相同的组织学特征。两者之间的组织学区分很困难，通常只能通过局部结构浸润或通过神经周围或血管浸润来区分。作者描述了一例 69 岁男性患者，其腭部小唾液腺有一个巨大的 BCAC，该肿瘤向鼻腔和翼腭窝进展，并通过上颌骨次全切除术进行治疗。这是一个高度局部进展的病例，需要比其他先前报道的腭部小唾液腺 BCAC 病例更广泛的手术切除范围。在这种情况下，仅凭局部活检可能无法做出正确的诊断。应该记住，仅凭活检标本的显微镜检查可能难以区分 BCAC 与基底细胞腺瘤。
