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单脉冲 TMS 对加法和乘法右顶叶和左顶叶皮层的干扰。

Single pulse TMS induced disruption to right and left parietal cortex on addition and multiplication.

机构信息

Basque Center on Cognition Brain and Language, Donostia, Spain.

出版信息

Neuroimage. 2012 Feb 15;59(4):3159-65. doi: 10.1016/j.neuroimage.2011.10.093. Epub 2011 Nov 4.

DOI:10.1016/j.neuroimage.2011.10.093
PMID:22079504
Abstract

Whether or not mathematical operations are dependent on verbal codes in left hemisphere areas - particularly the left intraparietal sulcus - remains an issue of intense debate. Using single pulse transcranial magnetic stimulation directed at horizontal and ventral regions of the left and right intraparietal sulcus, we examined disruption to reaction times in simple addition and multiplication. Results indicate that these two operations differ in the pattern of lateralization across time for the two areas studied. These show that computational efficiency is not specifically dependent on left hemisphere regions and, in particular, that efficiency in multiplication is dependent on the ventral region of the intraparietal sulcus in the right hemisphere considered to be critical for motion representation and automatization.

摘要

数学运算是否依赖于左半球区域的语言代码——尤其是左顶内沟——仍然是一个激烈争论的问题。使用单个脉冲经颅磁刺激作用于左右顶内沟的水平和腹侧区域,我们研究了对简单加法和乘法反应时间的干扰。结果表明,这两种操作在两个研究区域的时间上表现出不同的偏侧化模式。这表明计算效率并不特定依赖于左半球区域,特别是乘法效率依赖于被认为对运动表示和自动化至关重要的右半球顶内沟的腹侧区域。

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