The Helen Schneider Hospital for Women, Rabin Medical Center, Tel Aviv University Sackler School of Medicine, Petah Tikva, Israel.
Int J Gynecol Cancer. 2011 Dec;21(9):1704-7. doi: 10.1097/IGC.0b013e31822fa8a1.
Treatment of some cancers diagnosed at an early stage with expectation of prolonged survival has permitted the consideration of salvaging the reproductive and hormonal function of premenopausal female patients. When radiation to the pelvic area is part of treatment, this will almost always result in ovarian failure. To protect the ovaries, an oophoropexy may be performed, which involves moving the ovaries away from the radiation field. This procedure may be performed via laparoscopy. Some women undergoing laparoscopic radical hysterectomy may also be candidates for laparoscopic transposition. Because failure rates are still reported to be high, we developed a novel technique to mobilize the adnexa, which we present in this paper and attached movie.After separating the adnexa from the uterus and developing the infundibulopelvic (IP) ligament, a retroperitoneal tunnel is developed from the pelvis to the transposition opening laterally. The adnexa are moved through this tunnel, avoiding torsion of the vessels, and are brought through the opening back into the peritoneum. The adnexa are now fixed securely to the posterolateral abdominal wall with nonabsorbable sutures.Several issues permit better results using this technique. The IP ligament remains retroperitoneal and itself is outside the field of radiation. There is no kinking of the ovarian blood supply on the peritoneal fold. The location of the transposition is way above the field of radiation, preventing scatter injury. Even if one or both of the sutures fail, placement of the ovary will not change because of the peritoneum it has been brought through. This and the final location of the IP ligament retroperitoneally may enforce the ovary to it outside of the radiation field and prevent possible migration of the ovary back to the pelvis. This technique has advantages, which may offer the ovaries a better chance to resume hormonal function.
对于一些早期诊断且预期生存时间较长的癌症患者,治疗方法允许考虑保留绝经前女性患者的生殖和激素功能。当盆腔区域的放射治疗成为治疗的一部分时,这几乎肯定会导致卵巢衰竭。为了保护卵巢,可以进行卵巢固定术,即将卵巢从放射野中移开。该手术可通过腹腔镜进行。一些接受腹腔镜根治性子宫切除术的女性也可能是腹腔镜转位术的候选者。由于失败率仍有报道,我们开发了一种新的附件活动技术,本文介绍并附有操作视频。在将附件与子宫分离并分离出输卵管卵巢(IP)韧带后,从骨盆向侧面的转位开口发展出一个腹膜后隧道。将附件通过该隧道移动,避免血管扭转,并通过开口将其带回腹膜腔。然后,将附件牢固地固定在腹膜后外侧腹壁上,使用不可吸收缝线。
使用这种技术可以解决几个问题,从而获得更好的效果。IP 韧带保持在腹膜后,本身就在放射野外。卵巢血供不会在腹膜褶皱处发生扭曲。转位的位置远高于放射野外,防止散射损伤。即使一根或两根缝线失效,由于卵巢已通过腹膜穿过,其位置也不会改变。这和 IP 韧带最终腹膜后的位置可能会将卵巢固定在放射野外,防止卵巢可能迁移回盆腔。该技术具有优势,可为卵巢恢复激素功能提供更好的机会。