Université du Québec à Montréal, Montréal, QC, Canada.
J Clin Exp Neuropsychol. 2011 Nov;33(9):972-81. doi: 10.1080/13803395.2011.589372. Epub 2011 Jul 18.
Less efficient glucose regulation, the ability to metabolize glucose, has been associated with poorer cognitive performances in older individuals not meeting criteria for type 2 diabetes ( Messier, Tsiakas, Gagnon, & Desrochers, 2010 ). Yet, the influence of glucose regulation on attentional functions, which are sensitive to aging, is still unclear. The present study examined the relationship between glucose regulation and performances on attentional tasks in nondiabetic older adults. Twenty-two participants (60 years and older) were tested on neuropsychological tests of attention (Trail Making test, modified Stroop test) and on a computerized dual task, after receiving a 50-g glucose drink. Participants with the worse glucose regulation committed more errors on the switching condition of the modified Stroop test (p < .05) and tended to make more errors in divided-attention trials of the computerized dual task (p = .05). Altogether, these results suggest that glucose regulation may transiently influence performances of metabolically healthy older adults on tasks requiring switching attention.
葡萄糖调节效率较低,即代谢葡萄糖的能力,与不符合 2 型糖尿病标准的老年人认知表现较差有关(Messier、Tsiakas、Gagnon 和 Desrochers,2010 年)。然而,葡萄糖调节对注意力功能的影响(注意力功能对衰老敏感)仍不清楚。本研究探讨了葡萄糖调节与非糖尿病老年成年人注意力任务表现之间的关系。22 名参与者(60 岁及以上)在接受 50 克葡萄糖饮料后,接受了注意力的神经心理学测试(Trail Making 测试、改良 Stroop 测试)和计算机化双重任务的测试。葡萄糖调节较差的参与者在改良 Stroop 测试的转换条件下犯的错误更多(p <.05),并且在计算机化双重任务的分散注意力试验中更容易犯错误(p =.05)。总的来说,这些结果表明,葡萄糖调节可能会暂时影响代谢健康的老年成年人在需要转换注意力的任务上的表现。