Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Notre-Dame Hospital, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.
Head Neck. 2013 Apr;35(4):E115-8. doi: 10.1002/hed.21938. Epub 2011 Nov 15.
Cervical lymph node metastases of meningioma represent an important diagnostic and treatment challenge. Not only has this entity been rarely described, but successful treatment has never been reported in the literature.
This case report was conducted using reviews of the literature. A 58-year-old man with a history of resected anaplastic meningioma was referred for a right neck mass. Excisional biopsy revealed metastatic meningioma, and a metastatic workup was negative. Modified radical neck dissection showed positivity in 5 lymph nodes. The patient received adjuvant intensity-modulated radiation therapy (IMRT), for a mean target dose of 60 Gray (Gy). Two years after treatment, the patient was disease free. Eleven cases of cervical lymph node metastasis of meningioma were identified in our literature search, and none described successful treatment of this entity.
Cervical lymph node metastasis of anaplastic meningioma is potentially treatable with surgical resection and IMRT, although further studies with long-term follow-up are necessary.
脑膜瘤的颈部淋巴结转移是一个重要的诊断和治疗挑战。不仅这种情况很少被描述，而且文献中从未报道过成功的治疗方法。
本病例报告通过文献复习进行。一名 58 岁的男性，有切除的间变性脑膜瘤病史，因右颈部肿块就诊。切除活检显示转移性脑膜瘤，转移性检查为阴性。改良根治性颈淋巴结清扫术显示 5 个淋巴结阳性。患者接受了辅助强度调制放疗（IMRT），平均靶剂量为 60 戈瑞（Gy）。治疗 2 年后，患者无疾病。我们的文献检索中发现了 11 例脑膜瘤颈部淋巴结转移病例，均未描述该疾病的成功治疗方法。
采用手术切除和 IMRT 治疗间变性脑膜瘤的颈部淋巴结转移具有潜在的可治疗性，尽管需要进一步进行长期随访的研究。
