D-氨基葡萄糖-4-磷酸和1-胸腺嘧啶基-D-氨基葡萄糖-4,6-二硫酸盐的生物活性衍生物的合成。
Synthesis of biologically active derivatives of D-glucosamine-4-phosphate and 1-thyminyl-D-glucosamine-4,6-disulfate.
作者信息
Idegami K, Ikeda K, Achiwa K
机构信息
School of Pharmaceutical Sciences, University of Shizuoka, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1990 Jun;38(6):1766-8. doi: 10.1248/cpb.38.1766.
PMID:2208395
Abstract
New 1-thyminyl-D-glucosamine-4-phosphate and 1-thyminyl-D-glucosamine-4,6-disulfate derivatives were synthesized. The 1-thyminyl-D-glucosamine-4,6-disulfate derivative showed antiviral activity against HIV.
摘要
合成了新的1-胸腺嘧啶基-D-氨基葡萄糖-4-磷酸酯和1-胸腺嘧啶基-D-氨基葡萄糖-4,6-二硫酸酯衍生物。1-胸腺嘧啶基-D-氨基葡萄糖-4,6-二硫酸酯衍生物显示出对HIV的抗病毒活性。
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