Ohta Hiromitsu, Miyauchi Eisaku, Ebina Masahito, Nukiwa Toshihiro
Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Clin Med Insights Case Rep. 2011;4:29-33. doi: 10.4137/CCRep.S7180. Epub 2011 Jun 13.
A 59-year-old man presented with a skin eruption and bilateral swelling of the legs. Soon after the initial presentation, he developed acute respiratory distress syndrome (ARDS) with miliary lung nodules. Culture of samples from the skin ulcers, sputum, and bronchoalveolar lavage fluid all revealed Mycobacterium szulgai infection. The patient was successfully treated with antituberculosis drugs. M. szulgai infection is very rarely reported worldwide, and disseminated infection usually occurs in immunocompromised patients. However, the present patient was a non-immunocompromised case, although he was a hepatitis B virus carrier. While the progression to ARDS from M. tuberculosis infection is well known, this is the first case of M. szulgai infection progressing to ARDS.
一名59岁男性出现皮肤疹和双腿双侧肿胀。初次就诊后不久,他发展为急性呼吸窘迫综合征(ARDS)并伴有粟粒性肺结节。皮肤溃疡、痰液和支气管肺泡灌洗 fluid样本的培养均显示出szulgai分枝杆菌感染。该患者接受抗结核药物治疗成功。szulgai分枝杆菌感染在全球范围内报道极少,播散性感染通常发生在免疫功能低下的患者中。然而,本例患者虽为乙肝病毒携带者,但并非免疫功能低下病例。虽然结核分枝杆菌感染进展为ARDS是众所周知的,但这是首例szulgai分枝杆菌感染进展为ARDS的病例。