Ruoff Carl, Hanna Louay, Zhi Wanqing, Shahzad Ghulamullah, Gotlieb Vladimir, Saif Muhammad Wasif
New York Hospital Medical Center of Queens, Flushing, NY 11355, USA.
ISRN Oncol. 2011;2011:728579. doi: 10.5402/2011/728579. Epub 2011 Aug 11.
Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. It is generally recommended that right hemicolectomy is the preferred treatment for adenocarcinoma of appendix. The role of chemotherapy is unclear due to lacking randomized trials but seems to be accepted if there is lymph node involvement or peritoneal seeding.
阑尾癌很罕见。大多数是在因阑尾炎进行阑尾切除术时意外发现的。经检查,大多数肿瘤为类癌、腺瘤和淋巴瘤。阑尾腺癌仅占所有癌症的0.08%,其治疗仍存在争议。在此,我们报告一名46岁男性,表现为阑尾炎症状,被诊断为阑尾腺癌。该患者接受了阑尾切除术,拒绝进一步手术以完成半结肠切除术。截至目前,他仍无症状。我们对阑尾肿瘤进行了文献综述。大多数良性疾病仅通过手术治疗。淋巴瘤需要类似CHOP方案的化疗,类癌综合征则用生长抑素类似物治疗。一般建议右半结肠切除术是阑尾腺癌的首选治疗方法。由于缺乏随机试验,化疗的作用尚不清楚,但如果有淋巴结受累或腹膜种植,似乎是可以接受的。