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阑尾癌的脑转移:罕见髓样癌组织学的综合回顾与报告

Cerebral Metastases in Appendiceal Cancer: Comprehensive Review and Report of Rare Medullary Carcinoma Histology.

作者信息

Mackel Charles, Rosenberg Harry, Varma Hemant, Vega Rafael, Stippler Martina

机构信息

Department of Neurosurgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

出版信息

Brain Tumor Res Treat. 2022 Jul;10(3):200-205. doi: 10.14791/btrt.2022.0019.

DOI:10.14791/btrt.2022.0019
PMID:35929119
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9353166/
Abstract

Appendiceal cancer is an extremely rare malignancy, and its metastatic spread to the brain is even more unusual. We describe a 47-year-old female who presented with a rare cerebral appendiceal carcinoma metastasis, a case that is further remarkable for representing the first histologic diagnosis of primary medullary carcinoma in the appendix. Based on a comprehensive review of the English literature using PubMed, Embase, and Google Scholar, only six other cases of cerebral appendiceal metastases have been described.

摘要

阑尾癌是一种极其罕见的恶性肿瘤,其转移至脑部的情况更为罕见。我们报告一例47岁女性,她患有罕见的阑尾癌脑转移,该病例的特别之处还在于这是阑尾原发性髓样癌的首例组织学诊断。通过使用PubMed、Embase和谷歌学术对英文文献进行全面检索,仅发现另外6例阑尾癌脑转移的病例报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/63672a8e48f7/btrt-10-200-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/79eccf45c474/btrt-10-200-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/16945201f98f/btrt-10-200-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/d8c165c6577d/btrt-10-200-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/63672a8e48f7/btrt-10-200-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/79eccf45c474/btrt-10-200-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/16945201f98f/btrt-10-200-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/d8c165c6577d/btrt-10-200-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45ce/9353166/63672a8e48f7/btrt-10-200-g004.jpg

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Cerebral Metastases in Appendiceal Cancer: Comprehensive Review and Report of Rare Medullary Carcinoma Histology.阑尾癌的脑转移:罕见髓样癌组织学的综合回顾与报告
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本文引用的文献

1
Case series on high grade appendiceal cancer with peritoneal and liver carcinomatosis undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).关于接受细胞减灭术和腹腔内热灌注化疗(HIPEC)治疗的伴有腹膜和肝转移瘤的高级别阑尾癌的病例系列研究。
Int J Surg Case Rep. 2022 May;94:107027. doi: 10.1016/j.ijscr.2022.107027. Epub 2022 Apr 4.
2
Incidence and predictors of brain metastasis in colorectal cancer patients.结直肠癌患者脑转移的发生率及预测因素。
Int J Colorectal Dis. 2022 Jan;37(1):153-159. doi: 10.1007/s00384-021-04041-2. Epub 2021 Oct 1.
3
Frequency and Risk Factors for Metastasis in Newly Diagnosed Appendiceal Carcinoma.
新诊断阑尾癌转移的频率及危险因素
Cureus. 2021 Jul 12;13(7):e16341. doi: 10.7759/cureus.16341. eCollection 2021 Jul.
4
Incidence and real-world burden of brain metastases from solid tumors and hematologic malignancies in Ontario: a population-based study.安大略省实体瘤和血液系统恶性肿瘤脑转移的发病率及真实世界负担:一项基于人群的研究。
Neurooncol Adv. 2020 Dec 22;3(1):vdaa178. doi: 10.1093/noajnl/vdaa178. eCollection 2021 Jan-Dec.
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Colorectal cancer statistics, 2020.2020 年结直肠癌统计数据。
CA Cancer J Clin. 2020 May;70(3):145-164. doi: 10.3322/caac.21601. Epub 2020 Mar 5.
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A study of appendiceal crypt cell adenocarcinoma (so-called goblet cell carcinoid and its related adenocarcinoma).阑尾隐窝细胞腺癌(所谓的杯状细胞类癌及其相关腺癌)的研究。
Hum Pathol. 2018 Feb;72:18-27. doi: 10.1016/j.humpath.2017.08.005. Epub 2017 Aug 18.
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Diagnosing colorectal medullary carcinoma: interobserver variability and clinicopathological implications.结直肠髓样癌的诊断:观察者间差异及临床病理意义
Hum Pathol. 2017 Apr;62:74-82. doi: 10.1016/j.humpath.2016.12.013. Epub 2016 Dec 26.
8
Systematic review: brain metastases from colorectal cancer--Incidence and patient characteristics.系统评价:结直肠癌脑转移——发病率及患者特征
BMC Cancer. 2016 Apr 1;16:260. doi: 10.1186/s12885-016-2290-5.
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Medullary colorectal carcinoma revisited: a clinical and pathological study of 102 cases.髓样结直肠癌再探讨:102例临床与病理研究
Ann Surg Oncol. 2015 Sep;22(9):2988-96. doi: 10.1245/s10434-014-4355-5. Epub 2015 Jan 9.
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Medullary carcinoma of the colon: can the undifferentiated be differentiated?结肠髓样癌:未分化型能被鉴别出来吗?
Virchows Arch. 2015 Jan;466(1):13-20. doi: 10.1007/s00428-014-1675-6. Epub 2014 Oct 23.