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肾移植前供体肾尿路结石的腔内泌尿外科处理

Endourological Management of Urolithiasis in Donor Kidneys prior to Renal Transplant.

作者信息

Vasdev Nikhil, Moir John, Dosani Muhammed T, Williams Robert, Soomro Naeem, Talbot David, Rix David

机构信息

Department of Urology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK.

出版信息

ISRN Urol. 2011;2011:242690. doi: 10.5402/2011/242690. Epub 2011 Jun 22.

Abstract

Background. We present our centres successful endourological methodology of ex vivo ureteroscopy (EVFUS) in the management of these kidneys prior to renal transplantation. Patient and Methods. A retrospective analysis was performed of all living donors (n = 157) identified to have asymptomatic incidental renal calculi from January 2004 until December 2008. The incidence of asymptomatic renal calculi was 3.2% (n = 5). Donors were subdivided into 2 groups depending on whether theydonated the kidney with the renal calculus (Group 1) versus the opposite calculus-free kidney (Group 2). Results. All donors in Group 1 underwent a left laparoscopic donor nephrectomy. The calculi were extracted in all 3 cases using a 7.5 Fr flexible ureteroscope either prior to transplant (n = 2) or on revascularization (n = 1). There were no urological complications in either group. At a mean followup at 64 months there was no recurrent calculi formation in the recipient in Group 1. However, 1 recipient formed a calculus in group 2 at a follow up of 72 months. Conclusions. Renal calculi can be successfully retrieved during living-related transplantation at the time of transplant itself using EVUS. This is technically feasible and is associated with no compromise in ureteral integrity or renal allograft function.

摘要

背景。我们展示了我们中心在肾移植前处理这些肾脏时成功的体外输尿管镜检查(EVFUS)的腔内泌尿外科方法。患者与方法。对2004年1月至2008年12月期间所有被确定患有无症状偶然肾结石的活体供者(n = 157)进行回顾性分析。无症状肾结石的发生率为3.2%(n = 5)。根据供者捐赠的是有肾结石的肾脏(第1组)还是相对无结石的肾脏(第2组),将供者分为两组。结果。第1组的所有供者均接受了左侧腹腔镜供肾切除术。在所有3例中,使用7.5 Fr的软性输尿管镜在移植前(n = 2)或血管重建时(n = 1)取出了结石。两组均无泌尿外科并发症。在平均64个月的随访中,第1组的受者未出现复发性结石形成。然而,第2组有1名受者在72个月的随访时形成了结石。结论。使用EVUS可以在亲属活体肾移植时成功取出肾结石。这在技术上是可行的,并且不会损害输尿管完整性或肾移植功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac34/3195395/3991b4c3a0ca/UROLOGY2011-242690.001.jpg

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