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Total synthesis of the potent androgen receptor antagonist (-)-arabilin: a strategic, biomimetic [1,7]-hydrogen shift.
J Am Chem Soc. 2011 Dec 21;133(50):20149-51. doi: 10.1021/ja209459f. Epub 2011 Nov 29.
2
Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp. MK756-CF1.
J Antibiot (Tokyo). 2010 Oct;63(10):601-5. doi: 10.1038/ja.2010.98. Epub 2010 Aug 25.
3
Antagonizing the Androgen Receptor with a Biomimetic Acyltransferase.
ACS Chem Biol. 2016 Oct 21;11(10):2797-2802. doi: 10.1021/acschembio.6b00659. Epub 2016 Aug 26.
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2-(2,2,2-Trifluoroethyl)-5,6-dichlorobenzimidazole derivatives as potent androgen receptor antagonists.
Bioorg Med Chem Lett. 2007 Feb 15;17(4):955-8. doi: 10.1016/j.bmcl.2006.11.047. Epub 2006 Nov 18.
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Synthesis and SAR of potent and selective androgen receptor antagonists: 5,6-Dichloro-benzimidazole derivatives.
Bioorg Med Chem Lett. 2007 Feb 1;17(3):784-8. doi: 10.1016/j.bmcl.2006.10.071. Epub 2006 Oct 28.
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Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones.
Bioorg Med Chem Lett. 2007 Mar 15;17(6):1523-6. doi: 10.1016/j.bmcl.2007.01.007. Epub 2007 Jan 13.
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Anti-androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor.
Bioorg Med Chem Lett. 2003 Aug 18;13(16):2655-8. doi: 10.1016/s0960-894x(03)00575-4.

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Enantio- and Diastereoselective Copper-Catalyzed Allylboration of Alkynes with Allylic gem-Dichlorides.
Angew Chem Int Ed Engl. 2022 Jun 7;61(23):e202117696. doi: 10.1002/anie.202117696. Epub 2022 Mar 21.
2
Decarboxylative and dehydrative coupling of dienoic acids and pentadienyl alcohols to form 1,3,6,8-tetraenes.
Beilstein J Org Chem. 2017 Feb 28;13:384-392. doi: 10.3762/bjoc.13.41. eCollection 2017.
3
Arabilin overcomes resistance to AR-targeted therapy.
J Antibiot (Tokyo). 2017 Mar;70(3):328-330. doi: 10.1038/ja.2016.162. Epub 2017 Jan 11.
4
Total synthesis of kingianin A.
Org Lett. 2013 Jan 18;15(2):398-401. doi: 10.1021/ol303388k. Epub 2012 Dec 28.

本文引用的文献

1
Targeting continued androgen receptor signaling in prostate cancer.
Clin Cancer Res. 2011 Jun 15;17(12):3876-83. doi: 10.1158/1078-0432.CCR-10-2815.
2
Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp. MK756-CF1.
J Antibiot (Tokyo). 2010 Oct;63(10):601-5. doi: 10.1038/ja.2010.98. Epub 2010 Aug 25.
4
Total synthesis and evaluation of phostriecin and key structural analogues.
J Org Chem. 2010 Nov 19;75(22):7505-13. doi: 10.1021/jo1010203. Epub 2010 Jul 29.
5
The total synthesis of (-)-SNF4435 C and (+)-SNF4435 D.
J Am Chem Soc. 2004 Dec 15;126(49):15968-9. doi: 10.1021/ja044733l.
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DFT study of pericyclic reaction cascades in the synthesis of antibiotic TAN-1085.
Org Lett. 2004 Nov 11;6(23):4273-5. doi: 10.1021/ol048277h.
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Concise total synthesis and structure assignment of TAN-1085.
Angew Chem Int Ed Engl. 2004 Jun 14;43(24):3167-71. doi: 10.1002/anie.200453801.
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Studies on the biomimetic synthesis of SNF4435 C and D.
Org Lett. 2002 Oct 17;4(21):3731-4. doi: 10.1021/ol020157r.
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Synthetic studies toward SNF4435 C and SNF4435 D.
Org Lett. 2002 Jun 27;4(13):2221-4. doi: 10.1021/ol026069o.

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