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[辅助性癌症治疗:患者认为何种益处值得追求?]

[Adjuvant cancer treatment: what benefit does the patient consider worthwhile?].

作者信息

Pieterse Arwen H, Stalmeier Peep F, Kroep Judith R, Stiggelbout Anne M

机构信息

Leids Universitair Medisch Centrum, Leiden, the Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2011;155(45):A3905.

Abstract

Adjuvant treatments can be added to primary curative cancer treatments to increase the probability of survival. However, these treatments have side effects. Research into what additional probability of survival cancer patients require from an adjuvant treatment before they consider it worthwhile, has been carried out in hypothetical situations. The published literature on this subject shows that the additional benefit which patients expect is small. Yet, variation in patient preferences within studies is large. Preferences regarding additional benefit are not consistently associated with patient socio-demographic or disease characteristics. It is very likely that new patients who face the choice of adjuvant treatment will greatly differ from each other in the benefit that they require from it. In order to give individualized recommendations, specialists need to ask the patient which benefits and disadvantages he or she considers to be important.

摘要

辅助治疗可以添加到癌症的主要根治性治疗中,以提高生存率。然而,这些治疗有副作用。关于癌症患者在认为辅助治疗值得之前需要从辅助治疗中获得多高的额外生存概率的研究,是在假设情况下进行的。关于这一主题的已发表文献表明,患者期望的额外益处很小。然而,研究中患者偏好的差异很大。关于额外益处的偏好与患者的社会人口统计学或疾病特征没有始终如一的关联。面临辅助治疗选择的新患者很可能在他们对辅助治疗的需求益处方面彼此有很大差异。为了给出个性化的建议,专家需要询问患者他或她认为哪些利弊是重要的。

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