van Tienhoven Geertjan, Wilmink J W Hanneke
Academisch Medisch Centrum, Amsterdam, the Netherlands.
Ned Tijdschr Geneeskd. 2011;155(45):A4100.
A 60-year-old Ghanese woman was treated with radiotherapy and capecitabine for metastatic breast cancer. 6 weeks after starting capecitabine she developed palmar and plantar hyperpigmentation, which preceded symptoms of hand-foot syndrome, a known adverse effect of capecitabine. After a dose reduction, the hand-foot syndrome diminished but the hyperpigmentation remained. 8 months later the patient was well and stable.
一名60岁的加纳女性因转移性乳腺癌接受了放疗和卡培他滨治疗。开始使用卡培他滨6周后，她出现了掌跖色素沉着，这早于手足综合征的症状，而手足综合征是卡培他滨已知的不良反应。剂量减少后，手足综合征有所减轻，但色素沉着仍然存在。8个月后，患者情况良好且病情稳定。
