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小儿癫痫中迁移性障碍的神经影像学检查

Neuroimaging of migrational disorders in pediatric epilepsy.

作者信息

Taheri M Reza, Krauthamer Andres, Otjen Jeff, Khanna Paritosh C, Ishak Gisele E

机构信息

Department of Radiology, The George Washington University Hospital, Washington, DC, USA.

出版信息

Curr Probl Diagn Radiol. 2012 Jan-Feb;41(1):11-9. doi: 10.1067/j.cpradiol.2011.06.003.

Abstract

Seizures in children are common and represent a final pathway for a variety of brain insults. Although most children with seizures do not require imaging, when indicated, imaging plays an important role in the clinical workup. Imaging in the pediatric seizure population is reserved for a particular subset of patients depending on factors, such as age of onset, symptomatology, physical examination findings, and specific electroencephalography changes to name a few. The etiologies of seizures are extensive and include disorders of cortical migration and organization. Cortical migration and organization disorders are multifactorial and complex and a major cause of seizure disorders. Although magnetic resonance imaging is the most common imaging modality used to identify the seizure focus, positron emission tomographic and/or diffusion tensor imaging are beginning to provide complementary information about the involved areas. Early and accurate detection is key to better treatment and overall improved patient prognosis.

摘要

儿童癫痫发作很常见,是多种脑损伤的最终表现形式。虽然大多数癫痫发作的儿童不需要影像学检查,但在有指征时,影像学检查在临床检查中起着重要作用。根据发病年龄、症状、体格检查结果以及特定脑电图变化等因素,儿科癫痫患者群体中的影像学检查适用于特定的患者亚组。癫痫发作的病因广泛,包括皮质迁移和组织紊乱。皮质迁移和组织紊乱是多因素且复杂的,是癫痫疾病的主要原因。虽然磁共振成像(MRI)是用于确定癫痫病灶最常用的影像学检查方式,但正电子发射断层扫描(PET)和/或扩散张量成像(DTI)开始提供有关受累区域的补充信息。早期准确检测是更好治疗和改善患者总体预后的关键。

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