White P H
Department of Pediatric Rheumatology, Children's National Medical Center, George Washington University, Washington, D.C. 20010.
Clin Orthop Relat Res. 1990 Oct(259):46-50.
Growth abnormalities in juvenile rheumatoid arthritis can be divided into two groups: local and systemic. Local disorders of growth often result in increased bone length and bone age or in marked decreases in longitudinal growth due to immobilization, premature epiphyseal closure, or fusion. Common growth defects seen in the knee, hand, wrist, hip, spine, and jaw are discussed. Systemic growth delay is most commonly secondary to active disease or treatment with corticosteroids. Nutritional aspects such as decreased appetite, reduced caloric intake, metabolic caloric requirements greater than available intake, or lack of essential vitamins could be the cause for decreased weight and stature.
局部性和全身性。局部生长紊乱常导致骨长度增加、骨龄增长，或因固定、骨骺过早闭合或融合而导致纵向生长显著下降。文中讨论了在膝、手、腕、髋、脊柱和颌部常见的生长缺陷。全身性生长迟缓最常见的原因是活动性疾病或使用皮质类固醇治疗。营养方面的因素，如食欲减退、热量摄入减少、代谢所需热量大于可摄入热量或缺乏必需维生素，可能是体重和身高下降的原因。
