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一项针对苏格兰骨科医生在全髋关节置换患者中进行血栓预防实践的研究。新指南是否会改变实践?

A study of thromboprophylactic practices of Scottish orthopaedic surgeons in patients undergoing total hip replacements. Should practice change with new guidelines?

机构信息

StR Trauma and Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh EH16 4SU, Scotland, UK.

出版信息

Scott Med J. 2011 Nov;56(4):191-4. doi: 10.1258/smj.2011.011156.

Abstract

Despite increasing scientific investigation, the best method for preventing postoperative thromboembolism in patients undergoing a total hip replacement (THR) remains unclear. National Institute for Health and Clinical Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN) guidelines on the prevention of thromboembolism have caused much controversy. We surveyed Scottish surgeons regarding their thromboprophylaxis prescribing after THR. Questionnaires were sent to all Scottish orthopaedic consultants. They were asked about routine pharmacological and mechanical prophylaxis in patients undergoing a THR. Comparison was made with a previous survey done in 2003. The response rate was 75%. The survey showed an increased use of pharmacological prophylaxis from 93% to 100%. This was due to the increased use of aspirin from 51% to 64%. The use of low molecular weight heparin has remained constant at 51%. No surgeons routinely use warfarin, un-fractionated heparin or fondaparinux. Use of graded compression stockings has increased from 59% to 70%. In conclusion, there is increasing evidence that patients undergoing THR should receive extended prophylaxis for up to 35 days. Oral agents such as dabigatran and rivaroxaban have offered a new option for oral extended prescribing. The results in change of practice must be closely audited.

摘要

尽管科学研究不断增加,但对于接受全髋关节置换术 (THR) 的患者,预防术后血栓栓塞的最佳方法仍不清楚。国家卫生与临床优化研究所 (NICE) 和苏格兰校际指南网络 (SIGN) 关于预防血栓栓塞的指南引起了很多争议。我们调查了苏格兰外科医生在 THR 后的血栓预防处方情况。向所有苏格兰骨科顾问发送了问卷。他们被问及接受 THR 的患者的常规药物和机械预防措施。并与 2003 年进行的一项先前调查进行了比较。回复率为 75%。调查显示,药物预防的使用从 93%增加到 100%。这是由于阿司匹林的使用从 51%增加到 64%。低分子肝素的使用保持在 51%不变。没有外科医生常规使用华法林、未分级肝素或磺达肝素。分级压缩袜的使用从 59%增加到 70%。总之,越来越多的证据表明,接受 THR 的患者应接受长达 35 天的延长预防。达比加群和利伐沙班等口服药物为口服延长处方提供了新的选择。必须密切审核实践改变的结果。

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