Landau Jennifer L, Moody Megan N, Kazakevich Natalia, Goldberg Leonard H
DermSurgery Associates, Houston, TX, USA.
Skin Therapy Lett. 2011 Oct;16(9):1-3.
Pregnancy is characterized by multiple physiologic changes. During the entire gestational period, both mother and infant are vulnerable to a variety of external and internal factors. Maternal disease, use of certain medications, drugs, alcohol, smoking, and radiation exposure can have devastating effects on the fetus. Pregnancy-related complications in women with psoriasis can be caused by both the disease and the treatment. The response of the maternal placenta to psoriasis-induced inflammation and comorbid conditions, such as obesity, hypertension, and depression, may also influence the pregnancy. Herein, we review the relationship between psoriasis and undesirable pregnancy outcomes.
妊娠具有多种生理变化的特征。在整个妊娠期,母亲和婴儿都易受各种外部和内部因素的影响。母体疾病、某些药物的使用、毒品、酒精、吸烟以及辐射暴露都可能对胎儿产生毁灭性影响。银屑病女性的妊娠相关并发症可能由疾病本身和治疗引起。母体胎盘对银屑病诱发的炎症以及肥胖、高血压和抑郁症等合并症的反应也可能影响妊娠。在此,我们综述银屑病与不良妊娠结局之间的关系。