• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

重症肌无力作为肺癌患者的首发症状:一例病例报告。

Myasthenia gravis as a presenting feature in a patient with lung cancer: A case report.

作者信息

Shaygannejad Vahid, Ghasemi Majid, Rajaee Zahra

机构信息

Associate Professor, Department of Neurology, School of Medicine and Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

J Res Med Sci. 2011 Feb;16(2):229-32.

PMID:22091237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3214309/
Abstract

A male patient with muscle weakness had clinical findings of ptosis, diplopia, proximal leg weakness, and positive repetitive nerve stimulation (RNS) test. He demonstrated positive acetylcholine receptor antibody. This lung cancer patient was presenting myasthenia gravis. The causal association between non-small-cell lung cancer and non-thymomatous myasthenia gravis has not been clarified yet. To date, there has been no evidence supporting the speculation that association of myasthenia gravis with lung cancer might be one of the phenotypes of paraneoplastic syndrome.

摘要

一名患有肌无力的男性患者有上睑下垂、复视、近端腿部肌无力以及重复神经电刺激(RNS)试验阳性等临床表现。他的乙酰胆碱受体抗体呈阳性。这名肺癌患者表现出重症肌无力。非小细胞肺癌与非胸腺瘤性重症肌无力之间的因果关系尚未明确。迄今为止,尚无证据支持重症肌无力与肺癌的关联可能是副肿瘤综合征的一种表型这一推测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094a/3214309/1ad7f9ae1b8e/JRMS-16-229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094a/3214309/2ab3976d5a6b/JRMS-16-229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094a/3214309/1ad7f9ae1b8e/JRMS-16-229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094a/3214309/2ab3976d5a6b/JRMS-16-229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094a/3214309/1ad7f9ae1b8e/JRMS-16-229-g003.jpg

相似文献

1
Myasthenia gravis as a presenting feature in a patient with lung cancer: A case report.重症肌无力作为肺癌患者的首发症状:一例病例报告。
J Res Med Sci. 2011 Feb;16(2):229-32.
2
Lung cancer associated with seronegative myasthenia gravis.与血清阴性重症肌无力相关的肺癌
Intern Med. 2015;54(11):1381-4. doi: 10.2169/internalmedicine.54.3363. Epub 2015 Jun 1.
3
Myasthenia Gravis Related to Small Cell Lung Carcinoma.与小细胞肺癌相关的重症肌无力
Cureus. 2021 Mar 14;13(3):e13889. doi: 10.7759/cureus.13889.
4
5
[A case of small cell lung cancer that developed during therapy for myasthenia gravis].[1例在重症肌无力治疗期间发生的小细胞肺癌]
Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Apr;33(4):456-62.
6
Myasthenia gravis with a paraneoplastic marker.伴有副肿瘤标志物的重症肌无力
J Neuroophthalmol. 2000 Jun;20(2):102-5. doi: 10.1097/00041327-200020020-00008.
7
Myasthenia gravis and myopathy after nivolumab treatment for non-small cell lung carcinoma: A case report.尼伏鲁单抗治疗非小细胞肺癌后出现重症肌无力和肌病:一例报告。
Thorac Cancer. 2019 Oct;10(10):2045-2049. doi: 10.1111/1759-7714.13177. Epub 2019 Aug 21.
8
Childhood-onset myasthenia gravis with thymoma.儿童期起病的重症肌无力伴胸腺瘤。
Pediatr Neurol. 2012 May;46(5):329-31. doi: 10.1016/j.pediatrneurol.2012.02.025.
9
Ocular myasthenia gravis in an academic neuro-ophthalmology clinic: clinical features and therapeutic response.学术性神经眼科诊所中的眼肌型重症肌无力:临床特征与治疗反应
J Clin Neuromuscul Dis. 2011 Sep;13(1):46-52. doi: 10.1097/CND.0b013e31821c5634.
10
Case Series: A case of familial thymomatous myasthenia gravis in a family of three male brothers.病例系列:一个有三名男性兄弟的家庭中出现的一例家族性胸腺瘤型重症肌无力病例。
J Surg Case Rep. 2020 Sep 26;2020(9):rjaa321. doi: 10.1093/jscr/rjaa321. eCollection 2020 Sep.

引用本文的文献

1
The Association Between Myasthenia Gravis and Higher Extrathymic Cancer Risk.重症肌无力与胸外癌症高风险之间的关联。
Brain Behav. 2025 Jan;15(1):e70143. doi: 10.1002/brb3.70143.
2
Myasthenia Gravis as a Paraneoplastic Manifestation of Renal Cell Carcinoma: More Than a Coincidence?重症肌无力作为肾细胞癌的副肿瘤表现:仅是巧合?
Ann Neurosci. 2025 Jan;32(1):47-50. doi: 10.1177/09727531241306852. Epub 2025 Jan 13.
3
Myasthenia-like paraneoplastic syndrome with multiple cranial nerve tumor infiltration: A case report and literature review.

本文引用的文献

1
Coexistent autoimmune autonomic ganglionopathy and myasthenia gravis associated with non-small-cell lung cancer.共存的自身免疫性自主神经节病变和重症肌无力与非小细胞肺癌相关。
Muscle Nerve. 2010 Mar;41(3):416-9. doi: 10.1002/mus.21528.
2
Non-small-cell lung cancer associated with non-thymomatous myasthenia gravis.非小细胞肺癌合并非胸腺瘤性重症肌无力
Jpn J Thorac Cardiovasc Surg. 2006 May;54(5):207-11. doi: 10.1007/BF02670314.
3
Extrathymic malignancies in patients with myasthenia gravis.重症肌无力患者的胸腺外恶性肿瘤
伴多颅神经肿瘤浸润的类重症肌无力副肿瘤综合征:病例报告及文献复习。
Medicine (Baltimore). 2023 May 19;102(20):e33774. doi: 10.1097/MD.0000000000033774.
4
Myasthenia gravis that has developed long after radical resection of lung cancer: A case report.肺癌根治术后长期发生的重症肌无力:一例报告。
Exp Ther Med. 2022 Jul 5;24(3):554. doi: 10.3892/etm.2022.11492. eCollection 2022 Sep.
5
Myasthenia gravis associated with renal cell carcinoma: a paraneoplastic syndrome or just a coincidence.重症肌无力与肾细胞癌相关:副肿瘤综合征还是纯属巧合。
BMC Neurol. 2021 Jul 12;21(1):277. doi: 10.1186/s12883-021-02311-8.
6
Coexistence of myasthenia gravis and Lambert-Eaton myasthenic syndrome in a small cell lung cancer patient: A case report.一名小细胞肺癌患者合并重症肌无力和兰伯特-伊顿肌无力综合征:病例报告
Medicine (Baltimore). 2018 Jun;97(23):e10976. doi: 10.1097/MD.0000000000010976.
J Neurol Sci. 2005 Oct 15;237(1-2):39-43. doi: 10.1016/j.jns.2005.05.009.
4
Neuroendocrine lung tumors and disorders of the neuromuscular junction.
Neurology. 1999 Apr 22;52(7):1490-1. doi: 10.1212/wnl.52.7.1490.
5
Risk of cancer in patients with myasthenia gravis.重症肌无力患者患癌风险
Ann N Y Acad Sci. 1998 May 13;841:742-5. doi: 10.1111/j.1749-6632.1998.tb11011.x.
6
The association of malignancy with rheumatic and connective tissue diseases.恶性肿瘤与风湿性和结缔组织疾病的关联。
Semin Oncol. 1997 Jun;24(3):360-72.
7
Predictors of survival following surgical resection of thymoma.
J Surg Oncol. 1993 Dec;54(4):233-8. doi: 10.1002/jso.2930540409.
8
[A case of small cell lung cancer that developed during therapy for myasthenia gravis].[1例在重症肌无力治疗期间发生的小细胞肺癌]
Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Apr;33(4):456-62.
9
Observations of the natural history of myasthenia gravis and the effect of thymectomy.重症肌无力的自然病史观察及胸腺切除术的效果
Ann N Y Acad Sci. 1981;377:678-90. doi: 10.1111/j.1749-6632.1981.tb33766.x.
10
Myasthenia as an autoimmune disease: clinical aspects.重症肌无力作为一种自身免疫性疾病:临床方面
Ann N Y Acad Sci. 1966 Jan 26;135(1):517-35. doi: 10.1111/j.1749-6632.1966.tb45500.x.