Wang Y S, Jiang Y H, Hou Z Y
First Hospital of Beijing Medical University.
Chin Med J (Engl). 1990 Jun;103(6):497-502.
This article is to present the experience in 1,000 cases given intrathecal Iohexol injection during 1985-1988, including conventional myelography in 343 cases, conventional and CT myelography in 572, only CT myelography in 60 and CT cisternography in 25. No convulsions were observed. The frequency of headache was 11.6% and the total uncomfortable subjective reaction was 19.6% after intrathecal injection, but no serious complications were found. Because of very low frequency of side effects after this injection, most of the examinations can be made in the outpatient departments. In our clinical experience, Iohexol appears to be a myelographic contrast medium with diagnostic capabilities and less morbidity compared to Metrizamide. Thus Iohexol seems to be well suited for intrathecal injection and will replace metrizamide in this respect.
本文旨在介绍1985年至1988年期间1000例鞘内注射碘海醇的经验，其中包括343例行传统脊髓造影、572例行传统及CT脊髓造影、60例行单纯CT脊髓造影以及25例行CT脑池造影。未观察到惊厥。鞘内注射后头痛发生率为11.6%，总的主观不适反应为19.6%，但未发现严重并发症。由于该注射后副作用发生率极低，大多数检查可在门诊进行。根据我们的临床经验，与甲泛葡胺相比，碘海醇似乎是一种具有诊断能力且发病率较低的脊髓造影对比剂。因此，碘海醇似乎非常适合鞘内注射，并将在这方面取代甲泛葡胺。
