Department of Large Animal Medicine, University of Georgia, Athens, GA 30602, USA.
J Vet Intern Med. 2011 Nov-Dec;25(6):1221-30. doi: 10.1111/j.1939-1676.2011.00804.x. Epub 2011 Oct 7.
Pneumonia is a major cause of disease and death in foals. Rhodococcus equi, a gram-positive facultative intracellular pathogen, is a common cause of pneumonia in foals. This article reviews the clinical manifestations of infection caused by R. equi in foals and summarizes current knowledge regarding mechanisms of virulence of, and immunity to, R. equi. A complementary consensus statement providing recommendations for the diagnosis, treatment, control, and prevention of infections caused by R. equi in foals can be found in the same issue of the Journal.
肺炎是幼驹发病和死亡的主要原因。马红球菌是一种革兰阳性兼性细胞内病原体,是幼驹肺炎的常见病因。本文综述了马红球菌感染幼驹的临床表现,并总结了目前关于马红球菌毒力机制和免疫的相关知识。在本期杂志中还刊登了一份关于幼驹马红球菌感染的诊断、治疗、控制和预防的共识声明。