Department of Genitourinary Medicine, St George's Hospital, London, UK.
HIV Med. 2012 Feb;13(2):138-40. doi: 10.1111/j.1468-1293.2011.00948.x. Epub 2011 Nov 16.
There are several reported cases of vertically infected children presenting with advanced HIV infection in the UK. The children of women with HIV infection are at increased risk of being infected. There are few data available on the number of such children that are yet to be tested for HIV. This study looked at the HIV testing status of children whose mothers attend HIV services at three south-west London clinics.
Case notes of women attending the clinics from 1 January to 30 June 2009 were reviewed. When data were incomplete, women were prospectively interviewed.
Case notes of 605 women were reviewed; 478 women had 1107 children. The majority of women (386; 81%) were of Black African ethnicity. Sixty-one per cent (675 of 1107) of the children were known to have been tested for HIV. The children resident abroad were more likely to be untested compared with those resident in the UK; 186 of 255 (73%) vs. 246 of 852 (29%). A quarter (106 of 432) of the untested children were ≤ 18 years old; 49 (46%) of these were resident in the UK. The most common reason given by the mothers for not testing was a perceived 'unlikely risk'.
A significant number of children at risk of vertically transmitted HIV infection, including 49 children ≤ 18 years and resident in the UK, were identified through this study. The mothers are being encouraged to have these children tested and a multidisciplinary team involving adult and paediatric HIV healthcare professionals has been set up to negotiate and facilitate testing.
在英国，有几例报道的垂直感染儿童出现晚期 HIV 感染的病例。HIV 感染妇女的子女感染风险增加。关于尚未接受 HIV 检测的此类儿童的数量，数据很少。本研究调查了在伦敦西南部三家诊所接受 HIV 服务的母亲的子女的 HIV 检测状况。
回顾了 2009 年 1 月 1 日至 6 月 30 日期间就诊的妇女的病历。当数据不完整时，对妇女进行前瞻性访谈。
共回顾了 605 名妇女的病历；478 名妇女有 1107 名子女。大多数妇女（386 名；81%）为非裔黑人。61%（1107 名儿童中的 675 名）已知已接受 HIV 检测。居住在国外的儿童与居住在英国的儿童相比，更有可能未接受检测；255 名儿童中有 186 名（73%）居住在国外，852 名儿童中有 246 名（29%）。四分之一（432 名未检测儿童中的 106 名）年龄≤18 岁；其中 49 名（46%）居住在英国。母亲未进行检测的最常见原因是认为“不太可能有风险”。
通过这项研究，确定了大量存在垂直传播 HIV 感染风险的儿童，包括 49 名≤18 岁且居住在英国的儿童。鼓励这些儿童进行检测，并成立了一个由成人和儿科 HIV 保健专业人员组成的多学科小组，以协商和促进检测。
