National Center for Tumor Diseases Heidelberg, Germany.
Contemp Clin Trials. 2012 Mar;33(2):456-8. doi: 10.1016/j.cct.2011.10.009. Epub 2011 Nov 9.
This note addresses the questions of whether one should safeguard against a potential loss of power due to random variations of the accrual time, how this "insurance" can be formulated, and how much the sample size needs to be increased to obtain it.
本说明讨论了是否应该防范由于应计时间的随机变化而导致的潜在权力损失的问题，如何制定这种“保险”，以及需要增加多少样本量才能获得这种“保险”。
