Division of General Pediatrics, Department of Pediatric and Adolescent Medicine, Medical University Graz, Graz, Austria.
Pediatr Infect Dis J. 2012 Mar;31(3):312-4. doi: 10.1097/INF.0b013e31823d9490.
We retrospectively studied antibiotic resistance rates of H. pylori and their temporal changes in children. Resistance rates were 21.6% for both clarithromycin and metronidazole. There was no overall difference between children with or without migrational background. Resistance rates increased over time, and patients without migrational background showed a significant increase in metronidazole resistance. Our study emphasizes antibiotic resistance monitoring of H. pylori in children.
我们回顾性研究了儿童幽门螺杆菌的抗生素耐药率及其随时间的变化。克拉霉素和甲硝唑的耐药率均为 21.6%。有或没有移民背景的儿童之间没有总体差异。耐药率随时间增加,没有移民背景的患者甲硝唑耐药率显著增加。本研究强调了儿童幽门螺杆菌抗生素耐药性监测。